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440191

Hexamethyldisilazan

reagent grade, ≥99%

Synonym(e):

HMDS

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Größe/SKUVerfügbarkeitPreis
100 mL
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€ 79,60
1 L
Warenkorb auf Verfügbarkeit prüfen
€ 309,00

Über diesen Artikel

Lineare Formel:
(CH3)3SiNHSi(CH3)3
CAS-Nummer:
Molekulargewicht:
161.39
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
213-668-5
Beilstein/REAXYS Number:
635752
MDL number:

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grade

reagent grade

Quality Segment

assay

≥99%

form

liquid

refractive index

n20/D 1.407 (lit.)

bp

125 °C (lit.)

SMILES string

C[Si](C)(C)N[Si](C)(C)C

InChI

1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3

InChI key

FFUAGWLWBBFQJT-UHFFFAOYSA-N

General description

Hexamethyldisilane (HMDS) is a stable and effectivereagent for trimethylsilylation of hydrogen-labile substrates such as alcohols,amines, and carboxylic acids. It is commonly used for the protection of sensitivefunctional groups during chemical synthesis. Owing to its low cost, high vapor pressure, and safety, itis widely used as a precursor in chemical vapor deposition(CVD) reactions.

Application

Hexamethyldisilane (HMDS) can be used:
  • As a silylating agent in the trimethylsilylation of alcohols under nearly neutral reaction conditions.
  • To control the molecular weights of polypeptides during ring-opening polymerization of α-amino acid N-carboxyanhydrides.
  • To fabricate silicon carbonitride thin films by plasma-enhanced CVD.
  • For specimen preparation for scanning electron microscopy and the preparation of trimethylsilyl ethers from hydroxy compounds.

Features and Benefits

  • High chemicalstability and low molecular weight
  • Nontoxic andcost-effective reagent
  • Ammonia is theonly byproduct generated during silylation
  • Silylationreaction using HDMS is nearly neutral and does not need any precaution

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Dieser Artikel
8694421706952630
description

reagent grade, ≥99%

description

Wacker Chemie AG, ≥97.0% (GC)

description

98%

description

puriss., ≥98.5% (GC)

assay

≥99%

assay

≥97.0% (GC)

assay

98%

assay

≥98.5% (GC)

grade

reagent grade

grade

-

grade

-

grade

puriss.

form

liquid

form

liquid

form

liquid

form

liquid

refractive index

n20/D 1.407 (lit.)

refractive index

n20/D 1.407 (lit.)

refractive index

n20/D 1.422 (lit.)

refractive index

n20/D 1.377

bp

125 °C (lit.)

bp

125 °C (lit.)

bp

112-114 °C (lit.)

bp

101 °C (lit.)

Quality Level

300

Quality Level

200

Quality Level

100

Quality Level

200


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Piktogramme

FlameSkull and crossbones

Signalwort

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2

Lagerklasse

3 - Flammable liquids

Was ist los?

WGK 2

Flammpunkt (°F)

52.5 °F - closed cup

Flammpunkt (°C)

11.4 °C - closed cup

PSA (Persönliche Schutzausrüstung)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the storage temperature of this reagent?

    1 answer
    1. This product may be stored at room temperature. For products with no specified storage temperature given on the label or product page, ambient storage may be assumed. Products that require controlled temperature storage, such as refrigeration or freezer conditions, storage temperatures are published on the product label, Certificate of Analysis, the Safety Data Sheet (SDS).

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