379409

3-Hydroxy-1,2-dimethyl-4(1H)-pyridon

98%

• Synonym(e): Deferiprone
• Empirische Formel (Hill-System): C₇H₉NO₂
• CAS-Nummer: 30652-11-0
• Molekulargewicht: 139.15
• NACRES: NA.22
• PubChem Substance ID: 24863630
• UNSPSC Code: 12352100
• MDL number: MFCD00134497
• Assay: 98%
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: 98%
• form: powder
• mp: 272-275 °C (lit.)
• functional group: ketone
• storage temp.: room temp
• SMILES string: CN1C=CC(=O)C(O)=C1C
• InChI: 1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3
• InChI key: TZXKOCQBRNJULO-UHFFFAOYSA-N

Beschreibung

General description

3-Hydroxy-1,2-dimethyl-4(1H)-pyridone (Hdpp, Deferiprone) is a hydroxy ketone derivative. It reacts with uranyl salts [UO₂(NO₃)₂] in aqueous acidic solution to afford mono nuclear complexes ([UO₂(dpp)(Hdpp)₂(H₂O)]ClO₄). X-ray studies have been conducted to examine the structure and geometry of these complexes.

Application

3-Hydroxy-1,2-dimethyl-4(1H)-pyridone (OH-pyridone) may be used in the bacterial killing assays. It has been employed as hydroxyketone chelating agent and its cytotoxic action against oral human normal and tumor cell lines has been evaluated.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302
• Sicherheitshinweise: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves