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Sigma-Aldrich

6,7-Dimethyl-2,3-di(2-pyridyl)chinoxalin

98%

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About This Item

Empirische Formel (Hill-System):
C20H16N4
CAS-Nummer:
6627-38-9
Molekulargewicht:
312.37
EG-Nummer:
229-592-0
MDL-Nummer:
MFCD00006730
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24847727
NACRES:
NA.22

Assay

98%

Form

powder

mp (Schmelzpunkt)

191-193 °C (lit.)

SMILES String

Cc1cc2nc(-c3ccccn3)c(nc2cc1C)-c4ccccn4

InChI

1S/C20H16N4/c1-13-11-17-18(12-14(13)2)24-20(16-8-4-6-10-22-16)19(23-17)15-7-3-5-9-21-15/h3-12H,1-2H3

InChIKey

NACXMBPTPBZQHY-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

6,7-Dimethyl-2,3-di-(2-pyridyl)quinoxaline has been used as an internal standard to investigate the clinical pharmacokinetics of nelfinavir mesylate, a potent inhibitor of HIV-1 protease.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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B Louveau et al.
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A precise and accurate high-performance liquid chromatography (HPLC) quantification method of rifampicin in human plasma was developed and validated using ultraviolet detection after an automatized solid-phase extraction. The method was validated with respect to selectivity, extraction recovery, linearity, intra- and
E Y Wu et al.
Journal of chromatography. B, Biomedical sciences and applications, 695(2), 373-380 (1997-08-01)
Nelfinavir mesylate, a potent and orally bioavailable inhibitor of HIV-1 protease (Ki=2 nM), has undergone Phase III clinical evaluation in a large population of HIV-positive patients. A high-performance liquid chromatography analytical method was developed to determine the pharmacokinetic parameters of
Salmaan Kanji et al.
Clinical pharmacokinetics, 59(3), 327-334 (2019-09-01)
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Sara Baldelli et al.
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Recently, the European Medicines Agency (EMA) has released new guidelines on the validation of bioanalytical methods. In this work, we compared the analytical performance of 2 high-performance liquid chromatography with tandem mass spectrometry methods designed for the quantification of the

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