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2-Amino-6,8-dihydroxypurin
Synonym(e):
2-Amino-6,8-purinediol, 8-Hydroxyguanine
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About This Item
Empirische Formel (Hill-System):
C5H5N5O2
CAS-Nummer:
Molekulargewicht:
167.13
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
Empfohlene Produkte
Verunreinigungen
<10% acetic acid
SMILES String
Nc1nc(O)c2[nH]c(O)nc2n1
InChI
1S/C5H5N5O2/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H5,6,7,8,9,10,11,12)
InChIKey
CLGFIVUFZRGQRP-UHFFFAOYSA-N
Signalwort
Warning
H-Sätze
P-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
235.4 °F - closed cup
Flammpunkt (°C)
113 °C - closed cup
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Ana-Maria Chiorcea-Paquim et al.
Mikrochimica acta, 188(2), 58-58 (2021-01-29)
Oxidative DNA damage plays an important role in the pathogenesis of various diseases. Among oxidative DNA lesions, 8-oxoguanine (8-oxoG) and its corresponding nucleotide 8-oxo-2'-deoxyguanosine (8-oxodG), the guanine and deoxyguanosine oxidation products, have gained much attention, being considered biomarkers for oxidative
Ilinca Nicolae et al.
Experimental and therapeutic medicine, 17(2), 1012-1019 (2019-01-27)
Recent data suggest that severe psoriasis is an independent risk factor for chronic renal disease. In the present study, we investigated the role of related-purine derivatives as predictors of renal dysfunctions in patients with psoriasis. A prospective study was conducted
Jia Guo et al.
Nucleic acids research, 41(16), 7700-7712 (2013-06-19)
Oxidized bases in DNA have been implicated in cancer, aging and neurodegenerative disease. We have developed an approach combining single-cell gel electrophoresis (comet) with fluorescence in situ hybridization (FISH) that enables the comparative quantification of low, physiologically relevant levels of
Maura Costello et al.
Nucleic acids research, 41(6), e67-e67 (2013-01-11)
As researchers begin probing deep coverage sequencing data for increasingly rare mutations and subclonal events, the fidelity of next generation sequencing (NGS) laboratory methods will become increasingly critical. Although error rates for sequencing and polymerase chain reaction (PCR) are well
Sara Timpano et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(4), 5716-5728 (2019-01-17)
Multicellular organisms balance oxygen delivery and toxicity by having oxygen pass through several barriers before cellular delivery. In human cell culture, these physiologic barriers are removed, exposing cells to higher oxygen levels. Human cells cultured in ambient air may appear
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