115568

(S)-(−)-α-Methylbenzylamin

98%

• Synonym(e): (S)-(−)-1-Phenyl-ethylamin
• Lineare Formel: C₆H₅CH(CH₃)NH₂
• CAS-Nummer: 2627-86-3
• Molekulargewicht: 121.18
• Beilstein: 2204907
• EG-Nummer: 220-098-0
• MDL-Nummer: MFCD00064406
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24847225
• NACRES: NA.22

Eigenschaften

• Dampfdruck: 0.5 mmHg ( 20 °C)
• Assay: 98%
• Optische Aktivität: [α]20/D −39°, neat
• Optische Reinheit: ee: 98% (GLC)
• Brechungsindex: n20/D 1.526 (lit.)
• bp: 187 °C (lit.)
• Dichte: 0.94 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: C[C@H](N)c1ccccc1
• InChI: 1S/C8H11N/c1-7(9)8-5-3-2-4-6-8/h2-7H,9H2,1H3/t7-/m0/s1
• InChIKey: RQEUFEKYXDPUSK-ZETCQYMHSA-N

Beschreibung

Anwendung

Used in a one-pot, multi-component synthesis of a highly substituted, chiral pyrrole.

(S)-(-)-α-Methylbenzylamine along with 2-formylphenylboronic acid has been used in a derivatization protocol to analyze the enantiomeric excess of chiral diols.
It can also be used:

• In the diastereoselective synthesis of S-aminonitriles.
• As a chiral auxiliary in the synthesis of (S)-(-)-N-acetylcalycotomine or (R)-(+)-N-acetylcalycotomine.
• As a chiral building block in the asymmetric synthesis of 1-substituted tetrahydro-β-carbolines.

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H302,H311,H314
• P-Sätze: P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P361 + P364
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Skin Corr. 1B
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flammpunkt (°F): 158.0 °F - closed cup
• Flammpunkt (°C): 70 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter