SLC6A4
solute carrier family 6 (neurotransmitter transporter), member 4
Synonyme:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
Spezies:
Human SLC6A4 (6532), Mouse Slc6a4 (15567), Rat Slc6a4 (25553), domestic guinea pig Slc6a4 (100135619), naked mole-rat Slc6a4 (101705584), Domestic Rabbit SLC6A4 (100340600), Domestic Rabbit SLC6A4 (100351801), dog SLC6A4 (491184), domestic cat SLC6A4 (101091163), Horse SLC6A4 (100053721) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
- Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
- domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
Speziesreaktivität
mouse, rat
Anwendung
Anti-SLC6A4/5HTT/SERT antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, human, mouse, rat
Anwendung
ELISA
flow cytometry
immunofluorescence
flow cytometry
immunofluorescence
Anti-SLC6A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
Fluoxetin -hydrochlorid -Lösung, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Sertraline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
esiRNA
Produktnummer
Beschreibung
Spezies