D7071

Dapoxetine hydrochloride

≥98% (HPLC)

• Synonym(e): (S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride, S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride
• Empirische Formel (Hill-System): C₂₁H₂₃NO · HCl
• CAS-Nummer: 129938-20-1
• Molekulargewicht: 341.87
• MDL-Nummer: MFCD08272809
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329798842
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D +125 to +135°, c = 1 in methanol
• Lagerbedingungen: desiccated
• Farbe: white
• Löslichkeit: DMSO: ≥20 mg/mL
• Ersteller: Eli Lilly
• Lagertemp.: room temp
• SMILES String: Cl.CN(C)[C@@H](CCOc1cccc2ccccc12)c3ccccc3
• InChI: 1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1
• InChIKey: IHWDIQRWYNMKFM-BDQAORGHSA-N
• Angaben zum Gen: human ... SLC6A4(6532)

Beschreibung

Allgemeine Beschreibung

Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.

Biochem./physiol. Wirkung

Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe.

Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation

Leistungsmerkmale und Vorteile

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H319,H413
• P-Sätze: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable