Direkt zum Inhalt
Merck

MTNR1A

melatonin receptor 1A

Synonyme:
MEL-1A-R, MT1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4543) Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
  • Mouse(17773) melatonin receptor 1A
  • Rat(114211) melatonin receptor 1A
  • dog(482904) melatonin receptor 1A
  • sheep(443022) melatonin receptor 1A
  • chicken(396319) melatonin receptor 1A
  • naked mole-rat(101719975) melatonin receptor 1A
  • domestic guinea pig(100720785) melatonin receptor 1A
  • cow(539948) melatonin receptor 1A
  • domestic cat(101098297) melatonin receptor 1A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
6-Hydroxymelatonin, ,
Spezies
human
Ramelteon, ,
Spezies
human
Agomelatine, ≥98% (HPLC),
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Luzindole, ≥90%,
Spezies
human
Agomelatine, ≥98% (HPLC),
Spezies
human
Melatonin, powder, ≥98% (TLC),
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MTNR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Melatonin, powder, ≥98% (TLC),
Spezies
human

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
N-Acetyl-5-Hydroxytryptamin, ≥99% (HPLC), powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MTNR1A,
Spezies
human