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KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

Synonyme:
EAG, EAG1, Kv10.1, h-eag
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3756) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(16510) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Rat(65198) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • cow(281881) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • chicken(421381) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic cat(101093161) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • dog(490277) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Horse(100051219) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • sheep(101120348) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Domestic Rabbit(100340515) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic guinea pig(100719620) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • naked mole-rat(101706330) potassium voltage-gated channel, subfamily H (eag-related), member 1

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Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Levofloxacin, 98.0-102.0% anhydrous basis (HPLC),
Spezies
human
N-Desmethylclozapine, ,
Spezies
human
Sparfloxacin, ≥98.0% (HPLC),
Spezies
human
Trimethoprim, ≥98.5%,
Spezies
human, rat
Trimethoprim, ≥99.0% (HPLC),
Spezies
human, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-Potassium Channel Kv10.1 (EAG-1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Nitrendipin, >95%, powder,
Spezies
human, rat
Pimozid, ,
Spezies
human, mouse, rat
Nifedipin, ≥98% (HPLC), powder,
Spezies
rat, mouse, human
Chinidin, anhydrous,
Spezies
mouse, human, rat
Chinidin, crystallized, ≥98.0% (dried material, NT),
Spezies
mouse, human, rat