The storage temperature and solution stability after reconstitution in DMSO have not been tested. It is recommended to make the solution fresh upon usage.
Fortfahren mit
P1793
Pimozid
≥98% (TLC), powder, D₂ dopamine receptor antagonist
Synonym(e):
1-[1-[4,4-Bis(4-fluorphenyl)-butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-on
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
500 mg | Warenkorb auf Verfügbarkeit prüfen | € 168,00 |
1 g | Warenkorb auf Verfügbarkeit prüfen | € 170,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C28H29F2N3O
CAS-Nummer:
Molekulargewicht:
461.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
218-171-7
MDL number:
Form:
powder
Technischer Dienst
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Unterstützung erhaltenProduktname
Pimozid,
form
powder
Quality Segment
solubility
DMSO: 18 mg/mL(lit.), chloroform: 5 mg/mL, H2O: insoluble(lit.)
originator
Teva
storage temp.
2-8°C
SMILES string
Fc1ccc(cc1)C(CCCN2CCC(CC2)N3C(=O)Nc4ccccc34)c5ccc(F)cc5
InChI
1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
InChI key
YVUQSNJEYSNKRX-UHFFFAOYSA-N
Gene Information
human ... ABCB1(5243), CACNA1G(8913), CYP3A4(1576), DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356), HTR7(3363), KCNH1(3756), KCNH2(3757), OPRD1(4985)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Scnn1g(24768)
Biochem/physiol Actions
D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor; Ca2+ channel antagonist; antipsychotic
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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Dieser Artikel | |||
|---|---|---|---|
| description - | description European Pharmacopoeia (EP) Reference Standard | description United States Pharmacopeia (USP) Reference Standard | description pharmaceutical secondary standard, certified reference material |
| form powder | form - | form - | form - |
| Quality Level 200 | Quality Level - | Quality Level - | Quality Level 300 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
| solubility DMSO: 18 mg/mL(lit.), H2O: insoluble(lit.), chloroform: 5 mg/mL | solubility - | solubility - | solubility - |
| Gene Information human ... ABCB1(5243), CACNA1G(8913), CYP3A4(1576), DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356), HTR7(3363), KCNH1(3756), KCNH2(3757), OPRD1(4985) | Gene Information human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356) | Gene Information human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356) | Gene Information - |
| originator Teva | originator - | originator - | originator - |
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When dissolved in DMSO, at what temperature should I store the solution?
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