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CTSB

cathepsin B

Synonyme:
APPS, CPSB
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13030) cathepsin B
  • Rat(64529) cathepsin B
  • domestic guinea pig(100714169) cathepsin B
  • naked mole-rat(101709008) cathepsin B
  • dog(486077) cathepsin B
  • Horse(100060963) cathepsin B
  • domestic cat(101084873) cathepsin B
  • cow(281105) cathepsin B
  • sheep(780470) cathepsin B
  • chicken(396329) cathepsin B

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Speziesreaktivität
bovine, human, porcine
Anwendung
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Monoclonal Anti- Cathepsin B in Maus hergestellte Antikörper, clone CB59-4B11, purified from hybridoma cell culture,
Speziesreaktivität
human, rat
Anwendung
ELISA
immunohistochemistry

western blot
Anti-Cathepsin B, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, rat
Anwendung
immunohistochemistry
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
Spezies
human
Kalpain-Inhibitor I, ≥97% (TLC), powder,
Spezies
human
MG-132(R), ≥95% (HPLC),
Spezies
human
Diethylcyanamid, 99%,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Spezies
human
Cathepsin B, humane Leber, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Spezies
human
Cathepsin B aus Rindermilz, lyophilized powder, ≥10 units/mg protein,
Spezies
cow
Cathepsin B, humane Leber, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Spezies
human
Cathepsin B from human placenta, lyophilized powder, ≥5 units/mg protein,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Ctsb,
Spezies
mouse
MISSION® esiRNA, targeting human CTSB,
Spezies
human

Small Molecule - Substrate

Produktnummer
Beschreibung
Spezies
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride, ,
Spezies
mouse, human, rat