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ATP1A1

ATPase, Na+/K+ transporting, alpha 1 polypeptide

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(476) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(11928) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Rat(24211) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic cat(101083695) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Horse(100034139) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • dog(403992) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • chicken(396530) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Domestic Rabbit(100302415) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • sheep(443381) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • cow(282144) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • naked mole-rat(101697634) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic guinea pig(100192382) ATPase, Na+/K+ transporting, alpha 1 polypeptide

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Small Molecule - Activator

Produktnummer
Beschreibung
Spezies
Digitoxigenin, ,
Spezies
rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-Na+/K+ ATPase (α Subunit) antibody produced in mouse, clone M7-PB-E9, ascites fluid,
Speziesreaktivität
bovine, canine, chicken, human, mouse, pig, sheep
Anwendung
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
xenopus, canine, human, monkey, mouse, porcine, rabbit, rat, sheep
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-Na+/K+ ATPase alpha-3, from rabbit,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-Na+/K+-ATPase α-1-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
bovine, human, rat
Anwendung
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-phospho-ATP1 α1/Na+K+ ATPase1 (pSer23) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Melittin, ≥97% (HPLC), synthetic,
Spezies
mouse, rat, human
Digitoxin, ≥92% (HPLC), powder,
Spezies
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Digoxin, analytical standard,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
Spezies

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human ATP1A1,
Spezies
human
MISSION® esiRNA, targeting mouse Atp1a1,
Spezies
mouse