F-049

p-Fluorofentanyl solution

100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₂H₂₇FN₂O
• CAS Number: 90736-23-5
• Molecular Weight: 354.46
• MDL number: MFCD06411158
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 0.5 mL
• manufacturer/tradename: Cerilliant^®
• drug control: estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• InChI: 1S/C22H27FN2O/c1-2-22(26)25(20-10-8-19(23)9-11-20)21-13-16-24(17-14-21)15-12-18-6-4-3-5-7-18/h3-11,21H,2,12-17H2,1H3
• InChI key: KXUBAVLIJFTASZ-UHFFFAOYSA-N

Description

General description

para-Fluorofentanyl is an opioid analgesic being an analogue of fentanyl developed by Janssen Pharmaceutica in the 1960s. para-Fluorofentanyl potently activates the human μ; opioid receptor and is abused recreationally. A certified Snap-N-Spike^® solution suitable for use as starting material in calibrators and controls for para-Fluorofentanyl LC/MS or GC/MS testing methods in clinical toxicology, urine drug testing or forensic analysis applications.

Application

• Quantitative analysis of synthetic opioids: A study presents a quantitative LC-MS/MS method for analyzing p-Fluorofentanyl along with Xylazine, Fentanyl, and related compounds in postmortem blood, aiding forensic and pharmacological research in opioid toxicity (Truver et al., 2024).


• Detection in biological specimens: Research on the detection of Fentanyl, synthetic opioids including p-Fluorofentanyl, and ketamine in hair samples from American and Italian populations provides critical data for understanding patterns of opioid abuse and assisting in drug monitoring programs (Salomone et al., 2023).


• Innovative forensic techniques: A study introduces the use of pressure-sensitive adhesives and paper spray-mass spectrometry for the efficient collection and analysis of p-Fluorofentanyl and related compounds from shipping materials, highlighting advancements in forensic methodologies (Prunty et al., 2023).


• Pharmacological profile and toxicological assessment: An exploration of fentanyl analog structure-activity relationships including p-Fluorofentanyl examines the determinants of their potencies for antinociception versus respiratory depression, crucial for developing safer analgesic agents (Varshneya et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup