F-043

Flubromazepam

1.0 mg/mL in methanol, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₅H₁₀BrFN₂O
• CAS Number: 2647-50-9
• Molecular Weight: 333.16
• MDL number: MFCD22055975
• UNSPSC Code: 41116107
• PubChem Substance ID: 329799661
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: O=C1CN=C(C2=CC=CC=C2F)C3=C(C=CC(Br)=C3)N1
• InChI: 1S/C15H10BrFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
• InChI key: ZRKDDZBVSZLOFS-UHFFFAOYSA-N

Description

General description

Flubromazepam is a potent, long-acting novel psychoactive benzodiazepine with anxiolytic, anticonvulsant, muscle relaxant and hypnotic properties. Flubromazepam reportedly has a high addiction potential and risk of overdose. This certified Snap-N-Spike^® solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing.

Application

• Quantitative analysis of benzodiazepines: Flubromazepam was included in a validated LC-MS/MS method for quantifying 13 designer benzodiazepines in blood, highlighting its importance in forensic toxicology and psychoactive substance studies (Mei et al., 2019).


• Retrospective HRMS data application: Flubromazepam′s detection in complex drug mixtures via high-resolution mass spectrometry underscores its application in enhancing analytical methodologies for drug safety and pharmacological research (Partridge et al., 2018).


• Advanced chromatographic techniques: The compound was part of a study using ultra-high performance liquid chromatography coupled with high-resolution time-of-flight mass spectrometry, improving the precision in detecting benzodiazepine analogs within pharmaceutical and clinical research contexts (Tomková et al., 2017).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup