T6319

Anti-TOM22 antibody , Mouse monoclonal

clone 1C9-2, purified from hybridoma cell culture

• Sinónimos: Anti-Mitochondrial import receptor Tom22, Anti-TOMM22, Anti-Translocase of outer mitochondrial membrane 22 homolog (yeast)
• Número MDL: MFCD03457578
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• conjugado: unconjugated
• forma del anticuerpo: purified from hybridoma cell culture
• tipo de anticuerpo: primary antibodies
• clon: 1C9-2, monoclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 22 kDa
• reactividad de especies: human, monkey
• no debe reaccionar con: rodent
• concentración: ~1 mg/mL
• técnicas: immunocytochemistry: suitable; microarray: suitable; western blot: 0.5-1.0 μg/mL using whole extract of cultured human lymphoma Raji cells.
• isotipo: IgG1
• Nº de acceso UniProt: Q9NS69
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TOMM22(56993)

Descripción

Descripción general

Translocase of outer mitochondrial membrane 22 (TOMM22) is an essential receptor of the mitochondrial import channel. It is characterized with an N-terminal negatively charged region exposed to the cytosol, a putative transmembrane region and a C-terminal intermembrane space region with little negative charge.

Inmunógeno

membrane fraction from Vero (monkey kidney-derived) cells.

Aplicación

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

• Western blotting

Acciones bioquímicas o fisiológicas

Translocase of outer mitochondrial membrane 22 (TOMM22) is a key constituent of TOM complex. It functions as a mitochondrial receptor for the proapoptotic protein Bax (BCL2-associated X protein). TOMM22 interacts with 3-β hydroxysteroid dehydrogenase 2 (3βHSD2) and converts pregnenolone-to-progesterone in steroidogenic cells.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable