10602370001
Roche
Plasmin, bovine
from bovine plasma
Sinónimos:
Plasmin
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About This Item
Productos recomendados
origen biológico
bovine plasma
Formulario
suspension
actividad específica
≥2 units/mg protein (At 25 °C with Chromozym PL as the substrate.)
mol peso
Mr ~85 kDa
envase
pkg of 1 mL (5 U)
fabricante / nombre comercial
Roche
pH óptimo
8.9
Condiciones de envío
wet ice
temp. de almacenamiento
2-8°C
Descripción general
Plasmin is derived from the proteolytic cleavage of its precursor plasminogen. Human Plasmin is made up of two polypeptide chains. The polypeptide chains are connected via disulfide bridges.
Especificidad
Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.
Aplicación
Plasmin from bovine has been used as a standard for assessing plasmin biosensors and for proteolytic assays.
Acciones bioquímicas o fisiológicas
Plasmin plays an important role in proteolysis and fibrinolysis. It possesses inflammatory activity. Plasmin is also involved in the hydrolysis of peptide bonds following arginine or lysine. It also cleaves hormones like glucagon, thrombopoietin and growth hormones. Plasmin plays a role in cleavage of complement factors like C3 and C5, coagulation factors V and VIII, matrix proteins, growth factors, E-cadherins and metalloproteinase.
Forma física
Suspension in 3.2 M ammonium sulfate solution
Otras notas
For life science research only. Not for use in diagnostic procedures.
Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
does not flash
Punto de inflamabilidad (°C)
does not flash
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Plasmin-induced proteolysis and the role of apoprotein (a), lysine and synthetic lysine analogs
Rath M and Pauling L
Journal of Orthomolecular Medicine, 7(1), 17-23 (1992)
Chunyue Zhang et al.
Journal of dairy science, 103(1), 179-190 (2019-11-18)
Fat separation is a limiting factor for the shelf life of UHT milk. It may be promoted by the proteolysis of fat surface-adsorbed proteins (FSAP) by proteases that remain active after UHT treatment. The aim of this research was to
Plasmin as a proinflammatory cell activator
Syrovets T, et al.
Journal of Leukocyte Biology, 92(3), 509-519 (2012)
A rapid and sensitive biosensor for measuring plasmin activity in milk
Dacres H, et al.
Sensors and Actuators B, Chemical, 301, 127141-127141 (2019)
Primary structure of the B-chain of human plasmin
WIMAN B.
European Journal of Biochemistry, 76(1), 129-137 (1977)
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