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633267

Sigma-Aldrich

Dicyclohexylcarbodiimide solution

60 wt. % in xylenes

Sinónimos:

N,N′-Methanetetraylbis[cyclohexanamine], DCC, NSC 30022, NSC 53373, NSC 57182

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About This Item

Fórmula empírica (notación de Hill):
C13H22N2
Número de CAS:
538-75-0
Peso molecular:
206.33
MDL number:
MFCD00011659
UNSPSC Code:
12352200
PubChem Substance ID:
329759830
NACRES:
NA.22

reaction suitability

reaction type: Coupling Reactions

concentration

60 wt. % in xylenes

refractive index

n20/D 1.503

density

0.898 g/mL at 25 °C

SMILES string

C1CCC(CC1)N=C=NC2CCCCC2

InChI

1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2

InChI key

QOSSAOTZNIDXMA-UHFFFAOYSA-N

Application

Catalyst for Mitsunobu reaction to synthesize tetramethylpyrazine derivatives

Coupling agent for generation of graphene and graphene oxide sheets supported on silica

Endophytic bacterium L14 biomass inhibitor

Used to produce:
  • Multifunctional aqueous nanocrystals stabilized by hyperbranched polyglycerol
  • MnO2 nanosheets attached to Au nanoparticles on carbon nantubes
  • Functionalized single-walled carbon nantotube arrays

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system,Liver,Kidney, Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

86.0 °F

flash_point_c

30 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificados de análisis (COA)

Lot/Batch Number
MKBV2290V
MKBN3036V
MKBL6424V
MKBK6144V
MKBD3961

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Myo-inositol trispyrophosphate (ITPP), a synthetic allosteric effector of hemoglobin, increases the regulated oxygen-releasing capacity of red blood cells (RBCs), leading to suppression of hypoxia-inducible factor 1α (HIF-1α) and to down-regulation of hypoxia-inducible genes such as vascular endothelial growth factor (VEGF).
Andreia Biolo et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(6), 1926-1929 (2009-02-11)
A major determinant of maximal exercise capacity is the delivery of oxygen to exercising muscles. myo-Inositol trispyrophosphate (ITPP) is a recently identified membrane-permeant molecule that causes allosteric regulation of Hb oxygen binding affinity. In normal mice, i.p. administration of ITPP
Kenji Mizutani et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(33), 13474-13479 (2011-08-05)
The prokaryotic V-ATPase of Enterococcus hirae, closely related to the eukaryotic enzymes, provides a unique opportunity to study the ion-translocation mechanism because it transports Na(+), which can be detected by radioisotope (22Na(+)) experiments and X-ray crystallography. In this study, we
Daniel P Keeley et al.
Developmental cell, 54(1), 60-74 (2020-06-26)
Basement membranes (BMs) are supramolecular matrices built on laminin and type IV collagen networks that provide structural and signaling support to tissues. BM complexity, however, has hindered an understanding of its formation, dynamics, and regulation. Using genome editing, we tagged
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