Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

540056

Sigma-Aldrich

(R)-(−)-3-Chloro-1,2-propanediol

97%, optical purity ee: 98% (GLC)

Synonym(s):

(R)-α-Glycerol chlorohydrin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
ClCH2CH(OH)CH2OH
CAS Number:
57090-45-6
Molecular Weight:
110.54
Beilstein:
2202928
MDL number:
MFCD00135169
UNSPSC Code:
12352101
PubChem Substance ID:
24878435
NACRES:
NA.22

vapor pressure

0.04 mmHg ( 25 °C)

Assay

97%

optical activity

[α]20/D −1°, neat

optical purity

ee: 98% (GLC)

refractive index

n20/D 1.48 (lit.)

bp

213 °C (lit.)

density

1.321 g/mL at 20 °C (lit.)

functional group

chloro
hydroxyl

SMILES string

OC[C@@H](O)CCl

InChI

1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2/t3-/m0/s1

InChI key

SSZWWUDQMAHNAQ-VKHMYHEASA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Legal Information

Manufactured under license by Sterling Pharma Solutions Limited, using Jacobsen HKR technology.

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 1 Oral

Target Organs

Kidney

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

275.0 °F - closed cup

Flash Point(C)

135 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCJ4151
MKCH9802
MKBR2419V
MKBH1102V
MKBD3267

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Nithar Ranjan Madhu et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 30(2), 93-102 (2011-10-05)
To examine the effects of α-chlorohydrin on testis and cauda epididymis in the male house rat (Rattus rattus), 24 adult male rats were segregated into two groups. Group I rats were force-fed daily by intragastric intubation with α-chlorohydrin at a
Angus M Brown et al.
Journal of neurochemistry, 116(6), 996-1004 (2010-12-16)
We have previously shown that systemic administration of S(+)3-chloropropanediol (3-CPD) produces a morphological loss of astrocytes in specific nuclei of the rodent brain that precedes loss of both neurones and endothelial tight junctions. Here, we have evaluated the differential susceptibility
Brian D Craft et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(3), 354-361 (2011-12-16)
Recently, organic and inorganic chlorinated compounds were detected in crude and commercially refined palm oils. Further, the predominant formation mechanism of monochloropropanediol (MCPD) diesters at high temperatures (>170-180°C) was revealed. The present study involved the development and comparison of solutions
Shuwu Xie et al.
Reproductive biology and endocrinology : RB&E, 8, 37-37 (2010-04-23)
As one of the chlorinated antifertility compounds, alpha-chlorohydrin (ACH) can inhibit glyceraldehyde-3-phosphate dehydrogenase (G3PDH) activity in epididymal sperm and affect sperm energy metabolism, maturation and fertilization, eventually leading to male infertility. Further studies demonstrated that the inhibitory effect of ACH
Colin L Willis
Methods in molecular biology (Clifton, N.J.), 814, 515-529 (2011-12-07)
The goal of this chapter is to highlight methods used to demonstrate in vivo changes in astrocyte expression at the blood-brain barrier (BBB). Loss of BBB integrity is seen in many acute and chronic disease conditions. However, despite the importance
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service