69591

4-Methylumbelliferyl α-D-glucopyranoside

≥98% (TLC)

• Synonym(s): 4-Methylumbelliferyl α-D-glucoside
• Empirical Formula (Hill Notation): C₁₆H₁₈O₈
• CAS Number: 17833-43-1
• Molecular Weight: 338.31
• Beilstein: 1690776
• EC Number: 241-794-0
• MDL number: MFCD00067661
• UNSPSC Code: 12352204
• PubChem Substance ID: 57652200
• NACRES: NA.25

Properties

• description: α-glucosidase substrate
• Quality Level: 200
• Assay: ≥98% (TLC)
• form: powder
• solubility: DMSO: 50 mg/mL, clear, colorless to faintly yellow
• fluorescence: λ_ex 316 nm; λ_em 375 nm (Reaction product); λ_ex 317 nm; λ_em 374 nm (pH9.0); λ_ex 360 nm; λ_em 449 nm; λ_ex 365 nm; λ_em 445 nm in 0.1 M Tris pH 8.0 (α-glucosidase)
• storage temp.: −20°C
• SMILES string: CC1=CC(=O)Oc2cc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12
• InChI: 1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/m1/s1
• InChI key: YUDPTGPSBJVHCN-JZYAIQKZSA-N

Description

General description

4-Methylumbelliferyl α-D-glucopyranoside is the fluorogenic substrate of alpha-glucosidase enzyme. 4-Methylumbelliferyl α-D-glucopyranoside, also known as 4MU- α-glc, upon reaction leads to the product 4MU, which emits at the peak of 440nm in the fluorescence spectra.

Application

4-Methylumbelliferyl α-D-glucopyranoside is used as a flurogenic substrate for the identification, characterization and kinetic analysis of α-D-glucosidase(s).4-Methylumbelliferyl α-D-glucopyranoside is used for high throughput screening experiments. It is suitable for the diagnosis of Pompe′s disease in kidney and leucocytes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves