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E2888

Sigma-Aldrich

Earle′s Balanced Salts

With sodium bicarbonate, liquid, sterile-filtered, suitable for cell culture

Synonym(s):

EBSS

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About This Item

MDL number:
UNSPSC Code:
12352207
NACRES:
NA.75

Quality Level

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

components

phenol red: 0.011 g/L
glucose: 1.0 g/L (Dextro)
NaHCO3: 2.2 g/L

shipped in

ambient

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General description

Balanced Salt solution participates in providing a buffer system to maintain the medium in optimum pH range (7.2-7.6), irrigating and diluting while maintaining the intra- and extracellular osmotic balance. It helps to maintain the normal cell metabolism by giving water and bulk inorganic ions. Balanced Salt solution provides the energy source for cell metabolism by supplying carbohydrates such as glucose.

Application

Earle′s Balanced Salts has been used:
  • to incubate hepatocellular carcinoma cell line
  • as a component of embryo culture medium for washing rabbit embryos
  • to culture mouse embryonic neuroretina

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Yunchen Le et al.
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Life science alliance, 3(5) (2020-04-03)
Osteosarcoma (OS) is a primary malignant bone neoplasm with high frequencies of tumor metastasis and recurrence. Although the Akt/PKB signaling pathway is known to play key roles in tumorigenesis, the roles of cyclin-dependent kinase-like 3 (CDKL3) in OS progression remain
Ling Li et al.
The Journal of biological chemistry, 292(33), 13774-13783 (2017-07-15)
Autophagy has been shown to be important for normal homeostasis and adaptation to stress in the kidney. Yet, the molecular mechanisms regulating renal epithelial autophagy are not fully understood. Here, we explored the role of the stress-responsive transcription factor forkhead
Chinwendu Nwadike et al.
Molecular and cellular biology, 38(10) (2018-03-07)
Autophagy maintains metabolism in response to starvation, but each nutrient is sensed distinctly. Amino acid deficiency suppresses mechanistic target of rapamycin complex 1 (MTORC1), while glucose deficiency promotes AMP-activated protein kinase (AMPK). The MTORC1 and AMPK signaling pathways converge onto
Jun Song et al.
Scientific reports, 7(1), 12202-12202 (2017-09-25)
Immunodeficient mice have been used predominantly in biomedical research. Realizing that large animal species may have an enhanced ability to predict clinical outcome relative to mice, we worked to develop immunodeficient rabbits by CRISPR/Cas9. We first demonstrated that multiplex embryo

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