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403245

Sigma-Aldrich

(3-Carboxypropyl)trimethylammonium chloride

technical grade

Synonym(s):

γ-Butyrobetaine hydrochloride, Deoxycarnitine hydrochloride

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About This Item

Linear Formula:
C7H16NO2Cl
CAS Number:
6249-56-5
Molecular Weight:
181.66
MDL number:
MFCD00011905
UNSPSC Code:
12352116
PubChem Substance ID:
24864895
NACRES:
NA.22
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grade

technical grade

mp

220 °C (dec.) (lit.)

SMILES string

[Cl-].C[N+](C)(C)CCCC(O)=O

InChI

1S/C7H15NO2.ClH/c1-8(2,3)6-4-5-7(9)10;/h4-6H2,1-3H3;1H

InChI key

GNRKTORAJTTYIW-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000346989
0000346988
0000302452
0000234186
0000255959

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L M Henderson et al.
Federation proceedings, 41(12), 2843-2847 (1982-10-01)
The biosynthesis of carnitine proceeds from trimethyllysine (TML) by beta-hydroxylation by a liver or kidney mitochondrial enzyme, which requires oxygen, alpha-ketoglutarate, ferrous iron, and ascorbate. This dioxygenase is rapidly inactivated by preincubation with Fe2+, but not Fe3+. The evidence suggests
J S Serrano et al.
Methods and findings in experimental and clinical pharmacology, 5(4), 251-254 (1983-01-01)
The effects of GABA, its quaternary derivative N-trimethyl GABA and quinidine have been studied in a model of ventricular automaticity induced in the isolated right ventricle of the rat. GABA shows low anti-automatic activity. N-trimethyl GABA and quinidine were, however
W J Thoma et al.
Biochimica et biophysica acta, 797(1), 136-139 (1984-01-24)
The effect of ascorbate deficiency on carnitine biosynthesis was investigated in young male guinea pigs. Liver and skeletal muscle carnitine levels were reduced in scorbutic animals. Heart and kidney concentrations remained unchanged. 14C-labeled 4-N-trimethylaminobutyrate was administered to control, pair-fed and
Lisa Adamiak et al.
ACS nano, 11(10), 9877-9888 (2017-10-04)
Cellular uptake by macrophages and ensuing clearance by the mononuclear phagocyte system stands as a significant biological barrier for nanoparticle therapeutics. While there is a growing body of work investigating the design principles essential for imparting nanomaterials with long-circulating characteristics
Carnitine synthesis in scorbutic guinea pigs.
Nutrition reviews, 43(6), 185-187 (1985-06-01)
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