P3657

Pyridoxal 5′-phosphate hydrate

powder, BioReagent, suitable for cell culture

• Synonym(s): 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde, Codecarboxylase, PLP, Pyridoxal 5-phosphate
• Empirical Formula (Hill Notation): C₈H₁₀NO₆P · xH₂O
• CAS Number: 853645-22-4
• Molecular Weight: 247.14 (anhydrous basis)
• Beilstein: 234749
• EC Number: 200-208-3
• MDL number: MFCD00006333
• UNSPSC Code: 12352205
• PubChem Substance ID: 24898438
• NACRES: NA.75

Properties

• product line: BioReagent
• Assay: ≥98%
• form: powder
• mol wt: M_w 247.14 g/mol
• technique(s): cell culture | mammalian: suitable
• color: off-white to yellow-brown
• mp: 140-143 °C
• solubility: 1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green
• storage temp.: −20°C
• SMILES string: CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O
• InChI: 1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
• InChI key: NGVDGCNFYWLIFO-UHFFFAOYSA-N

Description

General description

Pyridoxal-phosphate (PLP, pyridoxal-5′-phosphate, P5P) is a prosthetic group of some enzymes. It is the active form of vitamin B6, which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. PLP acts as a coenzyme in all transamination reactions, and in some decarboxylation and deamination reactions of amino acids.

Application

• Hierarchical Surface Architecture of Hemodialysis Membranes for Eliminating Homocysteine Based on the Multifunctional Role of Pyridoxal 5′-phosphate.: Discusses the development of advanced hemodialysis membranes using pyridoxal 5′-phosphate, highlighting its role in reducing homocysteine levels, which could contribute to improved outcomes for dialysis patients (Jiang P et al., 2020).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves