535311
Poly(N-isopropylacrylamide)
Mn ~40,000
Synonym(s):
NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM
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About This Item
Linear Formula:
CH3(C6H11NO)nCH3
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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mol wt
Mn 20,000-60,000
Mn ~40,000
Quality Level
mp
96 °C
SMILES string
CC(C)NC(=O)C=C
InChI
1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)
InChI key
WDFKEEALECCKTJ-UHFFFAOYSA-N
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Application
Thermosensitive polymer, can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.
Physical form
Thermosensitive polymer, hydrogel
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Yan Xia et al.
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Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
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The aim of the present work is the use of a water soluble enzyme in an organic solvent, still with a pronounced catalytic activity. Therefore, lipase B from Candida antarctica (CalB) is immobilized within micron-sized thermosensitive p-NIPAM hydrogel particles using
Guiying Li et al.
International journal of biological macromolecules, 50(4), 899-904 (2012-06-09)
Thermo-sensitive poly(N-isopropyl acrylamide-co-vinyl pyrrolidone)/chitosan [P(NIPAM-co-NVP)/CS] semi-IPN hydrogels with improved loading capacity and sustained release for anionic drugs NAP were prepared by free-radical polymerization. The LCST of hydrogels was adjusted to the vicinity of body temperature by introducing hydrophilic NVP. The
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We report a novel approach for the fabrication of a photo-responsive surface with fast and reversibly switchable wettability between hydrophobicity and hydrophilicity induced by a photothermal effect.
Pengju Pan et al.
Langmuir : the ACS journal of surfaces and colloids, 28(40), 14347-14356 (2012-09-28)
Linear and miktoarm star-shaped diblock copolymers consisting of single-stranded DNA and poly(N-isopropylacrylamide) (PNIPAAm) with various compositions were synthesized via atom transfer radical polymerization and click chemistry. The temperature-responsive phase transition behavior, micellization, was systematically examined using UV-vis spectrometry, high-sensitivity differential
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