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440153

Sigma-Aldrich

L-α-lysophosphatidylinositol sodium salt

>99% (HPLC), powder, GPR55 agonist, Calbiochem®

Synonym(s):

L-α-lysophosphatidylinositol Sodium Salt, Soy, L-α-lysophosphatidylinositol LPI, Lyso PI, Soy Lyso PI

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About This Item

Empirical Formula (Hill Notation):
C25H48NaO12P
CAS Number:
796963-91-2
Molecular Weight:
594.61
UNSPSC Code:
12352200
NACRES:
NA.77

product name

L-α-lysophosphatidylinositol Sodium Salt, Soy, A potent agonist and assumed endogenous ligand of GPR55.

Quality Level

100

assay

>99% (HPLC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

color

white

solubility

DMSO: soluble

shipped in

ambient

storage temp.

−20°C

SMILES string

O[C@H]1[C@H](OP(OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O)([O-][Na+])=O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

General description

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.
A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Other Notes

Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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