Mucins are soluble in water, forming hazy viscous solutions.
M1778
Mucin from porcine stomach
Type III, bound sialic acid 0.5-1.5 %, partially purified powder
Synonym(s):
MUC
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$102.00
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$511.00
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10 G
$102.00
100 G
$511.00
About This Item
Recommended Products
biological source
Porcine stomach
Quality Level
type
Type III
form
partially purified powder
composition
bound sialic acid, 0.5-1.5%
technique(s)
microbiological culture: suitable
solubility
NaOH: soluble 20 mg/mL
storage temp.
2-8°C
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General description
Application
Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.[3]
Biochem/physiol Actions
Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.[4]
Preparation Note
Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
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Can I reconstitute the mucin so that it forms a saliva/snot-like substance? I can't seem to find any papers that have done this...
1 answer-
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How can I solubilize Product M1778, Mucin from porcine stomach?
1 answer-
Mucin is not readily soluble in aqueous solutions. Turbid "solutions" will form at about 5 mg/mL in 0.1 M acetate buffer, pH 5.0. To try to increase the solubility, one might try further dilution and sonication, but we have not tried this in our labs.
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What does the "Type" designation in Mucin from porcine stomach mean?
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The type designation does not have any particular biological significance. It is used to emphasize differences in the listings of this product.
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What is the molecular weight of Product M1778, Mucin from porcine stomach?
1 answer-
This product is partially purified from crude mucin, M2378. Sigma has not determined the molecular weight of this product. Neither has the sugar and amino acid composition been determined.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What are the differences between Mucin from porcine stomach Products M2378 and M1778?
1 answer-
Product No. M2378 is a crude mucin preparation. Product No. M1778 is a partially purified powder prepared according to the method described in Glenister, D.A. and Salmon. K. Microbial Ecol. in Health & Disease 1, 31, (1988). The amount of bound sialic acids are also different. Please refer to the specification sheets on our website.
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Is Product M1778, Mucin from porcine stomach, a purified preparation of mucin?
1 answer-
This product is a partially purified preparation of mucin based on the method of Glenister cited on the product's webpage.
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