Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

SRE0093

β-Glucuronidase from limpets (Patella vulgata)

aqueous solution

Synonym(s):

β-D-Glucuronide glucuronosohydrolase

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
10 mL

Available to ship TODAYfromMILWAUKEE

$197.00
25 mL

Available to ship TODAYfromMILWAUKEE

$455.00
50 mL

Available to ship TODAYfromMILWAUKEE

$822.00

About This Item

CAS Number:
9001-45-0
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
3.2.1.31 (BRENDA, IUBMB)
MDL number:
MFCD00130629
Recombinant:
expressed in proprietary host
Concentration:
100000-200000 units/mL

$197.00

Available to ship TODAYDetails

​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

recombinant

expressed in proprietary host

Quality Level

300

form

aqueous solution

concentration

100000-200000 units/mL

shipped in

ambient

storage temp.

2-8°C

Application

New Technical Article Comparing Performance of Different Enzymes
Learn more about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine
More on the suitability of this product for hydrolysis of different drug-glucuronide substrates is available at this page.
Poster presentation comparing the hydrolysis efficiency of novel beta-glucuronidase enzymes from recombinant limpet and recombinant E. coli sources, click at the following poster link: Hydrolysis Efficiency Evaluation of Novel Recombinant Limpet and E. coli Beta-Glucuronidase Enzymes
The enzyme from patella vulgata is reported to be more effective in hydrolyzing opioid-glucuronides than the Helix pomatia, bovine liver and E. coli enzymes

Features and Benefits

Recombinantly expressed and purified to eliminate MAM esterase activity (6-Monoacetylmorphine→morphine). Representative analysis at high enzyme titer (50 un/μL β-glucuronidase) was less than 1% conversion of 6-MAM to morphine after 4 hours at 60 °C.

Physical form

Supplied as a solution in 100mM potassium acetate pH 5.2. It is free of detergents, carbohydrates or any other components that may interfere with sample preparation and analysis.

Other Notes

One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 3.8 (30 min assay).

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
G8132G8885G0762
β-Glucuronidase from limpets (Patella vulgata) aqueous solution

Sigma-Aldrich

SRE0093

β-Glucuronidase from limpets (Patella vulgata)

β-Glucuronidase from limpets (Patella vulgata) Type L-II, lyophilized powder, 1,000,000-3,000,000 units/g solid

Sigma-Aldrich

G8132

β-Glucuronidase from limpets (Patella vulgata)

β-Glucuronidase from Helix pomatia Type H-3, aqueous solution, ≥90,000 units/mL

Sigma-Aldrich

G8885

β-Glucuronidase from Helix pomatia

β-Glucuronidase from Helix pomatia Type H-3AF, aqueous solution, ≥60,000 units/mL

Sigma-Aldrich

G0762

β-Glucuronidase from Helix pomatia

concentration

100000-200000 units/mL

concentration

-

concentration

-

concentration

-

recombinant

expressed in proprietary host

recombinant

-

recombinant

-

recombinant

-

form

aqueous solution

form

lyophilized powder

form

aqueous solution

form

aqueous solution

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

shipped in

ambient

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

300

Still not finding the right product?

Explore all of our products under β-Glucuronidase from limpets (Patella vulgata)

Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000479056
0000479055
0000479056
0000457165
0000457165

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Evaluation of Different Enzymes on Hydrolysis Efficiencies of Glucuronide Drug Metabolites in Urine

β-glucuronidase (GUS) enzymes are utilized to hydrolyze glucuronide (gluc) drug metabolites to the parent drug, facilitating analysis by LC-MS/MS.

Global Trade Item Number

SKUGTIN
SRE0093-1ML04061837151972
SRE0093-50ML04061831169386
SRE0093-10ML04061831169362
SRE0093-25ML04061831169379

Questions

Reviews

No rating value

Active Filters