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Anti-ZIP8 antibody produced in rabbit

Name: Anti-ZIP8 antibody produced in rabbit
Brand: SIGMA
Price: 580 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-BIGM103, Anti-PP3105, Anti-SLC39A8, Anti-Slc39A8, Anti-Solute carrier family 39 member A8

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Pack Size	SKU	Availability	Price
100 μg		Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$580.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$580.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

NP_071437

UniProt accession no.

Q9C0K1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SLC39A8(64116)

Description

General description

Solute carrier family 39 member 8 (SLC39A8), also known as zinc- and iron-related protein 8 (ZIP8), is a plasma membrane transporter protein. It is part of the solute carrier gene superfamily. The gene encoding SLC39A8 is localized on human chromosome 4q24.

Immunogen

ZIP8 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human ZIP8.

Application

Anti-ZIP8 antibody produced in rabbit has been used in immunocytochemistry.

Biochem/physiol Actions

Solute carrier family 39 member 8 (SLC39A8) co-transports divalent metal cations like cadmium, zinc, manganese and iron. It has a crucial role in the cellular uptake of cadmium. The protein is a target of nuclear-factor κB (NF-κB) and has a role in pro-inflammatory responses.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500598.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

1 of 1

This Item	SAB3500599	SAB3500596	SAB3500001
Sigma-Aldrich SAB3500598 Anti-ZIP8 antibody produced in rabbit	Sigma-Aldrich SAB3500599 Anti-ZIP9 antibody produced in rabbit	Sigma-Aldrich SAB3500596 Anti-ZIP5 antibody produced in rabbit	Sigma-Aldrich SAB3500001 Anti-ZIP11 antibody produced in rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level -	Quality Level 100
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Gene Information human ... SLC39A8(64116)	Gene Information human ... SLC39A9(55334)	Gene Information human ... SLC39A5(283375)	Gene Information human ... SLC39A11(201266)
species reactivity human	species reactivity mouse, human	species reactivity mouse, human	species reactivity rat, human, mouse

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

60951202

60951004

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Cellular localization and developmental
changes of Zip8, Zip14 and transferrin
receptor 1 in the inner ear of rats

Dalian Ding

Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, And Medicine (2014)

A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity.

Zhang R

Human Molecular Genetics (2016)

ZIP8 regulates host defense through zinc-mediated inhibition of NF-?B.

Liu MJ

Cell Reports (2013)

View All Related Papers

Global Trade Item Number

SKU	GTIN
SAB3500598-100UG	04061837874239

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