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Anti-LXR-B antibody produced in rabbit

Name: Anti-LXR-B antibody produced in rabbit
Brand: SIGMA
Price: 584 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-LXRB, Anti-Liver X receptor B, Anti-NR1H2, Anti-Nuclear receptor subfamily 1 group H member 2

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Pack Size	SKU	Availability	Price
100 μg		Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$584.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), WB

Citations:

$584.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human, rat

technique(s)

indirect ELISA: suitable, western blot: suitable

NCBI accession no.

P55055

UniProt accession no.

P55055

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NR1H2(7376)

Description

General description

Liver X receptor β (LXRβ ) is a member of LXRs that belong to the nuclear receptor superfamily. It possesses a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The protein is expressed in many tissues and the LXRβ gene is localized on human chromosome 19q13.3.

Immunogen

LXR-B antibody was raised against a 14 amino acid peptide from near the amino terminus human LXR-B.

Biochem/physiol Actions

Liver X receptor β (LXRβ) has a role in cell death and cholesterol metabolism. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500380.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB1404516	AV33672	AV38669
Sigma-Aldrich SAB3500380 Anti-LXR-B antibody produced in rabbit	Sigma-Aldrich SAB1404516 Monoclonal Anti-NR1H2 antibody produced in mouse	Sigma-Aldrich AV33672 Anti-NR1H4 antibody produced in rabbit	$Anti-NR1H3 antibody produced in rabbit IgG fraction of antiserum$ Sigma-Aldrich AV38669 Anti-NR1H3 antibody produced in rabbit
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form IgG fraction of antiserum
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level -	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
technique(s) indirect ELISA: suitable, western blot: suitable	technique(s) capture ELISA: suitable, indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: 1-5 μg/mL	technique(s) immunohistochemistry: suitable, western blot: suitable	technique(s) western blot: suitable
clone polyclonal	clone 1E1, monoclonal	clone polyclonal	clone polyclonal

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

55791001

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Liver x receptors in atherosclerosis and inflammation.

Im SS and Osborne TF

Circulation Research (2011)

Liver X receptor ? activation induces pyroptosis of human and murine colon cancer cells.

Derangere V

Cell Death and Differentiation (2014)

A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.

Mouzat K

BMC Medical Genetics (2011)

Global Trade Item Number

SKU	GTIN
SBP3500380-0.05MG	04061832161280
SAB3500380-100UG	04061832495804

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