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PRS4065

Anti-PD-1 (ab1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-CD279, Anti-PDCD1, Anti-Programmed cell death 1

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Pack SizeSKUAvailabilityPrice
100 μg
Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
$580.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, IHC, WB
Citations:
5

$580.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
A recombinant, preservative-free antibody is available for your target. Try ZRB1025
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 32 kDa

species reactivity

mouse, human

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

Q15116

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PDCD1(5133)

General description

PD-1 (programmed death-1) is an immunosuppressive molecule, which is also known as PDCD1 (programmed cell death 1). It is located on chromosome 2q37.3. It is a member of immunoglobulin receptor superfamily.

Immunogen

a 16 amino acid peptide from near the carboxy-terminus of human PD-1.

Biochem/physiol Actions

PD-1 (programmed death-1) gene is sensitive to systemic lupus erythematosus (SLE). Polymorphisms in PD-1 may participate in the growth of EOC (epithelial ovarian cancer). It acts as a negative regulator of T cells. It is also responsible for immune escape mediated by tumor cell.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP4065.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-PD-1 (ab1) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

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Anti-PD-1 Antibody, clone EH33 clone EH33.1F9.G4.5, from mouse

Sigma-Aldrich

MABC1122

Anti-PD-1 Antibody, clone EH33

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

biological source

rabbit

biological source

mouse

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... PDCD1(5133)

Gene Information

human ... PDCD1(5133)

Gene Information

human ... PDCD1(5133)

Gene Information

human ... PDCD1(5133)

UniProt accession no.

Q15116

UniProt accession no.

Q15116

UniProt accession no.

Q15116

UniProt accession no.

Q15116

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
40650604
4065-0604

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A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese
Kong EK, et al.
Arthritis and Rheumatism, 52(4), 1058-1062 (2005)
The effect of polymorphisms in PD-1 gene on the risk of epithelial ovarian cancer and patients' outcomes
Li Y, et al.
Gynecologic Oncology, 144(1), 140-145 (2017)
PD-1 and PD-L1 Expression Levels as a Potential Biomarker of Chronic Rhinosinusitis and Head and Neck Cancers.
Malinowska, et al.
Journal of clinical medicine, 12 (2023)
View All Related Papers

Global Trade Item Number

SKUGTIN
SBP4065-0.05MG04061832163062
PRS4065-100UG04061832509785

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