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PRS4059

Anti-PDL-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-B7-H1, Anti-CD274 molecule, Anti-Cardif, Anti-IPS-1, Anti-Programmed cell death 1 ligand-1

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Pack SizeSKUAvailabilityPrice
100 μg
Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
$580.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), FACS, IF, IHC, WB
Citations:
3

$580.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
A recombinant, preservative-free antibody is available for your target. Try ZRB1026
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 32 kDa

species reactivity

human, rat, mouse

technique(s)

flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

Q9NZQ7

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CD274(29126)

General description

PDL-1 (programmed cell death 1 ligand 1) is a cell surface protein, that is also known as B7-H1 (B7 homolog 1), coded by CD274 (cluster of differentiation 274) gene. It is located on chromosome 9p24.1. It is present on placental cells, vascular endothelial cells, liver cells, epithelial cells, mesenchymal stem cells, B cells, T cells, dendritic cells and macrophages. It is also expressed in various tumor types like melanoma, glioblastoma, cancers in the lung, kidney, head, neck, stomach, colon, pancreas, breast, cervix and ovary.

Immunogen

17 amino acid peptide from near the center of human PDL-1.

Biochem/physiol Actions

PDL-1 (programmed cell death 1 ligand 1) helps to clear sudden HPV (human papilloma virus) infections. It prevents the multiplication and adherence of T-cell and production of cytokine. It also controls the activities of T-cells in peripheral tissues.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP4059.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-PDL-1 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

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Anti-CD274/PD-L1 antibody produced in goat affinity isolated antibody, buffered aqueous solution

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Anti-PD-L1 Antibody, clone 29E.2A3.C6, Azide Free

Monoclonal Anti-PD-1 antibody produced in mouse clone 7A11B1, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

SAB3500122

Monoclonal Anti-PD-1 antibody produced in mouse

biological source

rabbit

biological source

goat

biological source

mouse

biological source

mouse

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, western blot: suitable, immunofluorescence: suitable, indirect ELISA: suitable

technique(s)

flow cytometry: suitable, immunofluorescence: suitable, indirect ELISA: suitable, western blot: suitable

technique(s)

flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), neutralization: suitable

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
40590604
4059-0604

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Prognostic significance of PD-L1 in solid tumor: An updated meta-analysis
Wang Q, et al.
Medicine, 96(18):e6369 (2017)
Association between PD-L1 and HPV status and the prognostic value for HPV treatment in premalignant cervical lesion patients
Yang-Chun F, et al.
Medicine, 96(25):e7270 (2017)
PD-1 and PD-L1 Expression Levels as a Potential Biomarker of Chronic Rhinosinusitis and Head and Neck Cancers.
Malinowska, et al.
Journal of clinical medicine, 12 (2023)

Global Trade Item Number

SKUGTIN
SBP4059-0.05MG04061832163055
PRS4059-100UG04061832509778

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