Although there are FDA approved drugs in the set, we market them based on their research application and not necessarily their therapeutic indications. All of the information we have is included on the CD that is received with the library. We do not include information from the Physician's Desk Reference.
LO4200
LOPAC®1280 - Small Scale
International Version
Synonym(s):
Library of Pharmacologically Active Compounds - small scale
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 ea | Check Cart for Availability | $8,240.00 |
About This Item
UNSPSC Code:
12352200
EC Number:
200-664-3
NACRES:
NA.77
Form:
liquid
Quality level:
Quality Level
form
liquid
drug control
Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
shipped in
dry ice
storage temp.
−20°C
General description
Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (25 μl at 10 mM in DMSO in archival storage racks).
Application
Library of pharmacologically active compounds LOPAC®1280 - small scale has been used to screen for the suppressors of niclosamide- and nigericin-induced interleukin (IL-1β) release.
Features and Benefits
Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:
- Apoptosis
- G Proteins & Cyclic Nucleotides
- Gene Regulation & Expression
- Ion Channels
- Lipid Signaling
- Multi-Drug Resistance
- Neurotransmission
- Phosphorylation
SDFile provided to construct a database containing:
- Structure
- Primary Name
- Secondary Name
- Pharmacological Activity
- Product Number
- Rack Position
Other Notes
For sale outside of the U.S. only. U.S. customers should refer to Product Code LO4100.
Legal Information
LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany
1 of 1
This Item | |||
|---|---|---|---|
| form liquid | form liquid | form liquid | form liquid |
| drug control Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet | drug control Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet | drug control Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet | drug control Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
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signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
188.6 °F
flash_point_c
87 °C
wgk
WGK 3
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Articles
Explore compound library screening options with our Pharmacologically Active Compounds portfolio.
Anzar Asad et al.
Basic & clinical pharmacology & toxicology, 133(4), 364-377 (2023-07-03)
Adhesion G protein-coupled receptors (GPCRs) are an underrepresented class of GPCRs in drug discovery. We previously developed an in vivo drug screening pipeline to identify compounds with agonist activity for Adgrg6 (Gpr126), an adhesion GPCR required for myelination of the
High-throughput screening identifies compounds that enhance lentiviral transduction.
Johnston JM, Denning G, Moot R, et al.
Gene Therapy, doi:10-doi:10 (2014)
Laura M Alcântara et al.
Molecules (Basel, Switzerland), 25(11) (2020-06-04)
High genetic and phenotypic variability between Leishmania species and strains within species make the development of broad-spectrum antileishmanial drugs challenging. Thus, screening panels consisting of several diverse Leishmania species can be useful in enabling compound prioritization based on their spectrum
Global Trade Item Number
| SKU | GTIN |
|---|---|
| LO4200-1EA | 04061833967256 |
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Are the LOPAC 1280 - Small Scale Products LO4100 and LO4200 approved for therapeutic use?
1 answer-
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Is the LOPAC 1280 - Small Scale Products LO4100 and LO4200 CD shipped with the product?
1 answer-
Yes, the CD is shipped with the product. If you do not receive it you should contact Sigma-Aldrich Technical Services at [email protected] or 1800-325-5832.
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What is on the LOPAC 1280 - Small Scale Products LO4100 and LO4200 CD?
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The CD contains the SDFile - provided to construct a database containing structure, primary name, secondary, Pharmacological Activity. Product number and Rack position.
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What is the difference between the LOPAC1280 Products LO4200 and LO1280?
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The compound per well in LO4200 is 25 ul at 10mM in DMSO versus 250 ul in the product LO1280.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Are the LOPAC 1280 - Small Scale Products LO4100 and LO4200 US approved?
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About 30% of the collection is made up of drugs approved for use in the US.
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What is the difference between the LOPAC1280 Products LO4100 and LO4200?
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These 2 products are the same. LO4100 is the US version versus LO4200 is the International version.
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Where can I find preparation instruction, storage and stability of the LOPAC 1280 - Small Scale Products LO4100 and LO4200?
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The information is available in the datasheet of a similar product LO1280.
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Can I get a list of CAS numbers of the drugs sent with LOPAC 1280 - Small Scale Products LO4100 and LO4200?
1 answer-
There is no CAS number list available.
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