There are no recommended pathologies for this product. This product is intended to be used as a standard in chemistry laboratory methods, primarily compendial monographs, and is not intended for administration to animals or humans. This product may not be used for therapeutic or diagnostic purposes for animals or humans.
PHR1541
Leucovorin Calcium
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Folinic acid calcium salt, Calcium folinate
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 g | Check Cart for Availability | $133.00 $113.05 |
About This Item
Empirical Formula (Hill Notation):
C20H21CaN7O7
CAS Number:
Molecular Weight:
511.50
UNSPSC Code:
41116107
EC Number:
216-082-8
NACRES:
NA.24
Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
USP 1358004, traceable to Ph. Eur. C0250000
API family
leucovorin
CofA
current certificate can be downloaded
packaging
ampule of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
[Ca+2].N1(C(CNc3nc(nc(c31)[O-])N)CNc2ccc(cc2)C(=O)N[C@@H](CCC(=O)[O-])C(=O)O)C=O
InChI
1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12?,13-;/m0./s1
InChI key
KVUAALJSMIVURS-ZEDZUCNESA-L
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Leucovorin Calcium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC1687 in the slot below. This is an example certificate only and may not be the lot that you receive.
1 of 1
This Item | |||
|---|---|---|---|
| application(s) pharmaceutical (small molecule) | application(s) pharmaceutical (small molecule) | application(s) pharmaceutical (small molecule) | application(s) pharmaceutical |
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - | technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable | technique(s) - |
| Quality Level 300 | Quality Level - | Quality Level - | Quality Level - |
| grade certified reference material, pharmaceutical secondary standard | grade pharmaceutical primary standard | grade pharmaceutical primary standard | grade pharmaceutical primary standard |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| packaging ampule of 1 g | packaging - | packaging - | packaging - |
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Oil-in-water microemulsion high performance liquid chromatographic analysis of pharmaceuticals.
Marsh A, et al.
Chromatographia, 59(9), 531-542 (2004)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| PHR1541-1G | 04061834420958 |
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