Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

904848

2-Chloro-1,3-bis(2,6-diisopropylphenyl)imidazolium chloride

≥95%

Synonym(s):

1,3-Bis(2,6-di-i-propylphenyl)-2-chloroimidazolium chloride, Chloroimidazolium chloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
500 mg

Available to ship TODAYfromMILWAUKEE

$164.00
2 g

Available to ship TODAYfromMILWAUKEE

$464.00

About This Item

Empirical Formula (Hill Notation):
C27H36Cl2N2
CAS Number:
1228185-09-8
Molecular Weight:
459.49
UNSPSC Code:
12352101
NACRES:
NA.22
MDL number:
MFCD23703069

$164.00

Available to ship TODAYDetails

​
Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥95%

form

powder

reaction suitability

reagent type: ligand

functional group

chloro

SMILES string

[Cl+]=C1N(C=CN1c3c(cccc3C(C)C)C(C)C)c2c(cccc2C(C)C)C(C)C.[Cl-]

InChI

1S/C27H36ClN2.ClH/c1-17(2)21-11-9-12-22(18(3)4)25(21)29-15-16-30(27(29)28)26-23(19(5)6)13-10-14-24(26)20(7)8;/h9-20H,1-8H3;1H/q+1;/p-1

InChI key

JDMACANGISWEGX-UHFFFAOYSA-M

Application

This chloroimidazolium chloride is used in the deoxyfluorination of phenols. Recently, the Ritter lab used it in conjunction with 902314 and 906794 to incorporate the [18F]fluoride radiolabel site specifically into polypeptides for use with positron emission tomography (PET) imaging in the study of various biological applications.

Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)

Other Notes

Site-specific deoxyfluorination of small peptides with [18F]fluoride

HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

18F-Deoxyfluorination of Phenols via Ru p-Complexes

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
244805696501715425
2-Chloro-1,3-bis(2,6-diisopropylphenyl)imidazolium chloride ≥95%

Sigma-Aldrich

904848

2-Chloro-1,3-bis(2,6-diisopropylphenyl)imidazolium chloride

Chromium(II) chloride 95%

Sigma-Aldrich

244805

Chromium(II) chloride

Chloro[1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]gold(I) 95%

Sigma-Aldrich

696501

Chloro[1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]gold(I)

Chloro[1,3-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]copper(I) 95%

Sigma-Aldrich

715425

Chloro[1,3-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]copper(I)

assay

≥95%

assay

95%

assay

95%

assay

95%

functional group

chloro

functional group

-

functional group

-

functional group

-

form

powder

form

powder

form

powder

form

powder

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCZ8140
MKCT1190
MKCJ8905
MKCT3587

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Related Content

Ritter Group – Professor Product Portal

The Ritter lab currently focuses on fluorination chemistry for late-stage functionalization of complex natural and unnatural products. PhenoFluor™ has been developed as a general reagent for the selective, predictable, direct deoxyfluorination of complex alcohols and phenols.

Martin G Strebl et al.
ACS central science, 3(9), 1006-1014 (2017-10-06)
Histone deacetylase 6 (HDAC6) function and dysregulation have been implicated in the etiology of certain cancers and more recently in central nervous system (CNS) disorders including Rett syndrome, Alzheimer's and Parkinson's diseases, and major depressive disorder. HDAC6-selective inhibitors have therapeutic
Teppei Fujimoto et al.
Organic process research & development, 18(8), 1041-1044 (2014-09-02)
We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope
Robert J Gilliard et al.
Chemical communications (Cambridge, England), 53(91), 12325-12328 (2017-11-03)
The reaction of the chloroimidazolium chloride salt, [NHC-Cl][Cl], NHC = C{N(2,6-iPr2C6H3)CH}2 (1) with two equivalents of sodium phosphaethynolate, Na[OCP]·(dioxane)2.5, results in the formation of NHC-{cyclo-(CO)-P2-C(O)} (2) and NHC-P2-C(O)-NHC (3). Notably, in the presence of free NHC ligand, compound 2 converts
View All Related Papers

Questions

Reviews

No rating value

Active Filters