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765112

Poly(L-lactide)

average Mn 10,000, PDI ≤1.1

Synonym(s):

PLA, PLLA, Polylactide, L-Lactide polymer, PLA, Poly(L-Lactic acid)

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5 g
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$267.00

About This Item

Linear Formula:
H(C3H4O2)nOCH3
NACRES:
NA.23
UNSPSC Code:
12162002

$267.00

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form

solid

Quality Level

100

optical activity

[α]22/D -150°, c = 0.5% in chloroform

mol wt

average Mn 10,000

degradation timeframe

>3 years

transition temp

Tm 162-167 °C

PDI

≤1.1

storage temp.

2-8°C

General description

Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.

Application

Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.

Features and Benefits

High initial strength, good strength retention and high amount of crystallinity, as much as 70%, which in turn is responsible for the very slow degradation rate.

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This Item
76469876459095468
Poly(L-lactide) average Mn 10,000, PDI ≤1.1

Sigma-Aldrich

765112

Poly(L-lactide)

Poly(L-lactide) average Mn 20,000, PDI ≤1.8

Sigma-Aldrich

764698

Poly(L-lactide)

Poly(L-lactide) average Mn 5,000, PDI ≤1.2

Sigma-Aldrich

764590

Poly(L-lactide)

Poly(L-lactide) viscosity ~4.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

95468

Poly(L-lactide)

form

solid

form

solid

form

solid

form

solid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

optical activity

[α]22/D -150°, c = 0.5% in chloroform

optical activity

[α]22/D -153°, c = 0.5% in chloroform

optical activity

[α]22/D -147°, c = 0.5% in chloroform

optical activity

-

degradation timeframe

>3 years

degradation timeframe

>3 years

degradation timeframe

>3 years

degradation timeframe

>3 years

transition temp

Tm 162-167 °C

transition temp

Tm 167-172 °C

transition temp

Tm 149-154 °C

transition temp

-

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX6744
MKCX2155
MKCN1975
MKCM5405
MKCG3203

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Articles

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Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

Bioprinting for Tissue Engineering and Regenerative Medicine

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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Chemical synthesis of polylactide and its copolymers for medical applications
Bendix, D.
Polymer Degradation and Stability, 59(1), 129-135 (1998)
Effect of poly (ethylene glycol)-block- poly (L-lactide) on the poly [(R)-3-hydroxybutyrate]/poly (L-lactide) blends
Yoon, J. S., Lee, W. S., Kim, K. S., Chin, I. J., Kim, M. N., & Kim, C.
Eur. Polymer J., 36(2), 435-442 (2000)
Synthesis and thermal properties of novel star-shaped poly (l-lactide)s with starburst PAMAM-OH dendrimer macroinitiator.
Zhao, Y. L., Cai, Q., Jiang, J., Shuai, X. T., Bei, J. Z., Chen, C. F., & Xi, F.
Polymer, 43(22), 5819-5825 (2002)
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Global Trade Item Number

SKUGTIN
765112-5G04061832923277

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