Skip to Content
MilliporeSigma

Skip To

763896

DL-α-Tocopherol methoxypolyethylene glycol succinate

greener alternative

powder

Synonym(s):

Polyethylene glycol, TPGS-750-M

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
1 g

Available to ship TODAYfromMILWAUKEE

$57.30
10 g

Available to ship TODAYfromMILWAUKEE

$381.00
25 g

Available to ship TODAYfromMILWAUKEE

$750.00
100 g

Available to ship TODAYfromMILWAUKEE

$1,480.00

About This Item

CAS Number:
MDL number:
NACRES:
NA.22
UNSPSC Code:
51171641

$57.30


Available to ship TODAYDetails


Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Product Name

DL-α-Tocopherol methoxypolyethylene glycol succinate,

form

powder

Quality Level

reaction suitability

reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

transition temp

Tm 29-34

greener alternative category

General description

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.

Application

DL-α-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M), a biodegradable and water-soluble derivative of natural vitamin E, is used as an environmentally benign nonionic surfactant in metal-catalyzed cross-coupling reactions in water. It is used in Heck, Suzuki-Miyaura, Sonogashira, and Negishi like couplings reactions. It can also be utilized in aminations, C-H activations, and olefin metathesis reactions.
TPGS-750-M can also be employed in:
  • The nucleophilic aromatic substitution reaction of aryl and heteroaryl halides with nitrogen, oxygen, and sulfur nucleophiles under mild conditions.
  • The preparation of quinoxaline-2,3 diones from quinoxalinones via C(sp2)-H hydroxylation reaction.
  • The intramolecular N-arylation of amines using a copper catalyst.

Other Notes

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
76391873385757668
form

powder

form

liquid

form

liquid

form

powder, crystals or chunks

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

reaction suitability

reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

reaction suitability

reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

reaction suitability

reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis, reagent type: surfactant

reaction suitability

-

sustainability

Greener Alternative Product

sustainability

Greener Alternative Product

sustainability

Greener Alternative Product

sustainability

-

transition temp

Tm 29-34

transition temp

-

transition temp

-

transition temp

-

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Protocols

TPGS-750-M surfactant enables various reactions in water at room temperature, enhancing efficiency and versatility in synthesis.

Articles

Micellular catalysis has provided the ability to carry out several commonly used transformations used in the synthetic community to be carried out in water.

Lipshutz and co-workers have recently developed a second generation technology to their original PTS-enabling surfactant based on the polyoxyethanyl-α-tocopheryl succinate derivative, TPGS-750-M.

Surfactants for efficient reactions in water as a green chemistry alternative.

View All Articles

Related Content

Designer surfactants enable diverse transformations like Suzuki-Miyaura, Olefin Metathesis, and 1,4-Addition to Enones in water by Prof. Bruce Lipshutz.


Metal-Free C3 Hydroxylation of Quinoxalin-2 (1H)-ones in Water
Peng S, et al.
Advanced Synthesis & Catalysis, 361(24), 5721-5726 (2019)
Nucleophilic aromatic substitution reactions in water enabled by micellar catalysis
Isley NA, et al.
Organic Letters, 17(19), 4734-4737 (2015)
Application of nanoparticle mediated N-arylation of amines for the synthesis of pharmaceutical entities using vit-E analogues as amphiphiles in water
Kumar A and Bishnoi AK
Royal Society of Chemistry Advances, 5(26), 20516-20520 (2015)



Global Trade Item Number

SKUGTIN
763896-100G04061842293056
763896-1G04061832922942
763896-25G04061833552230
763896-10G04061833340356

Questions

Reviews

No rating value

Active Filters