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34998

Acetonitrile

≥99.9%, HPLC Plus, suitable for IR spectroscopy, HPLC

Acetonitrile
1 of 1 reviewers took part in a promotion

Synonym(s):

Methyl cyanide, Anhydrous ACN, Dry MeCN

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1 L
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$367.00
2.5 L
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$547.00
4 L
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$714.00
4 x 4 L
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$2,430.00
20 L
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$3,330.00

About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
NACRES:
NA.03
PubChem Substance ID:
eCl@ss:
39031501
UNSPSC Code:
41116105
EC Number:
200-835-2
MDL number:
Beilstein/REAXYS Number:
741857
Assay:
≥99.9%
Grade:
HPLC Plus
Technique(s):
HPLC: suitable, IR spectroscopy: suitable
Bp:
81-82 °C (lit.)
Vapor pressure:
72.8 mmHg ( 20 °C)

$367.00


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Product Name

Acetonitrile, HPLC Plus, ≥99.9%

grade

HPLC Plus

Quality Level

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

assay

≥99.9%

form

liquid

autoignition temp.

973 °F

expl. lim.

16 %

baseline drift measuring range

≤12 mAU (210 nm)

technique(s)

HPLC: suitable, IR spectroscopy: suitable

impurities

≤0.0001% free alkali (as NH3), ≤0.0002% non-volatile matter, ≤0.001% free acid (as CH3COOH), ≤0.01% water (Karl Fischer), ≤0.5 ppb fluorescence (quinine) at 254 nm, ≤0.5 ppb fluorescence (quinine) at 365 nm

halogenated residue

10 ng/L (as heptachlor epoxide)

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

density

0.786 g/mL at 25 °C (lit.)

HPLC-gradient

≤0.2 mAU at 254 nm, ≤1 mAU at 210 nm

λ

H2O reference

UV absorption

λ: 195 nm Amax: ≤0.10, λ: 200 nm Amax: ≤0.02, λ: 228 nm Amax: ≤0.005, λ: 235 nm Amax: ≤0.0044, λ: 250 nm Amax: ≤0.0044, λ: 400 nm Amax: ≤0.0044

application(s)

food and beverages

format

neat

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

General description

Acetonitrile (MeCN) is widely employed as a solvent in various studies and has high dielectric constant (37.5). Various purification procedures to obtain different grades of acetonitrile for use in different studies (polarography, spectroscopy, etc.) have been reported by many researchers.

Application

Acetonitrile has been used to compose the gradient system for the HPLC detection of diphenylmethane diisocyanate, a polymeric degradation product.[1]
New Quality UPLC Plus Acetonitrile is suitable for all applications including:
Mass spectrometry, HPLC, TLC, GPC, UV, IR, GC, Pesticide Residue Analysis, and RNA/DNA Synthesis and Purification.

Packaging

M-Bottle for Solvents
As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here!

Preparation Note

Product filtered through a 0.2 μm filter

Other Notes

Important notice
  • The article number 34998-4X2.5L will be discontinued. Please order the single bottle 34998-2.5L which is physically identical with the same exact specifications.
  • The article number 34998-6X1L will be discontinued. Please order the single bottle 34998-1L which is physically identical with the same exact specifications.
Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.

Legal Information

Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
3485143913434881
grade

HPLC Plus

grade

gradient grade

grade

gradient grade

grade

HPLC grade

assay

≥99.9%

assay

≥99.9%

assay

≥99.9%

assay

≥99.8% (GC)

technique(s)

HPLC: suitable, IR spectroscopy: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, UV/Vis spectroscopy: suitable

technique(s)

HPLC-GC: suitable, HPLC: suitable, gas chromatography (GC): suitable

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

application(s)

food and beverages

application(s)

food and beverages

application(s)

food and beverages

application(s)

food and beverages

form

liquid

form

liquid

form

liquid

form

liquid


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pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup



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Certificates of Analysis (COA)

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Related Content

The 4L M-Bottle provides safe handling of solvents due to an innovative solvent bottle design with sealing technology to eliminate leaks and reduce risks in solvent dispensing.


H Haugen et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 73(2), 229-237 (2005-03-10)
This article deals with enzyme-induced biodegradation behavior of thermoplastic polyether-urethane (TPU). Porous scaffolds were processed by a new foaming method applied in hot pressing and injection molding. The scaffolds were subsequently gamma sterilized. The samples were incubated with cholesterol esterase
Alexander David Ardianrama et al.
Journal of colloid and interface science, 552, 485-493 (2019-06-04)
Although triangular silver (Ag) nanoplates are intrinsically unstable, this characteristic has been taken advantage of in the development of a novel sensing platform. However, most of these applications have relied on halide ions as etchants. In the current work, we
Purification of acetonitrile.
Walter M and Ramaley L.
Analytical Chemistry, 45(1), 165-166 (1973)



Global Trade Item Number

SKUGTIN
93845-50MG04061842113538
45466-250MG04061835560646
34998-200L-LS-NB04061837287244
34998-4X2.5L04061837478871
34998-180L04061837287220
34998-200L04061837287237
34998-20L-N204061837287251
34998-1L04061837478819
34998-2.5L04061837478826
34998-20L04061837478840
34998-395L04061837287275
34998-200L-P204061837478833
34998-20L-P204061837478857
34998-2X10L04061837287268
34998-50L-P2-LS04061837287299
34998-4X4L04061837478888
34998-4L04061837478864
34998-50L-P204061837287282

Questions

1–9 of 9 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. What kind of container is used for the 4L? Is a photo available?

    1 answer
    1. This product is packaged in a 4L amber glass bottle with a teflon-lined polypropylene screw cap. Unfortunately, an image is not available.

      Helpful?

  3. What kind of container is used for the 20L? Is a photo available?

    1 answer
    1. This product is packaged in a 20 liter HDPE drum. Please see the picture attached below.

      Helpful?

  4. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  5. What are the options for drying solvents?

    1 answer
    1. Sigma-Aldrich offers a full range of high-purity solvents with extremely low water levels specifically manufactured for moisture sensitive Organic and Biotech applications.  Sigma-Aldrich also carries various drying agents such as molecular sieves, which are typically compatible with organic solvents.

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  6. Who do I contact about larger solvent volume needs?

    1 answer
    1. Email us at [email protected] or visit Sigma-Aldrich Fine Chemicals for development and manufacturing-scale inquiries: [email protected]

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  7. Can you recommend a Solvent Extractor for organics from aqueous solution?

    1 answer
    1. Solvent extractors are often used for the quantitative extraction of organics from aqueous solutions and separations in immunoassays. The MIXXOR system has been applied successfully in many laboratory solvent extraction operations and is ideal for the rapid screening of alternative solvents for specific extraction problems.

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  8. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  9. What apparatus do you recommend for HPLC solvent filtration?

    1 answer
    1. The Sigma-Aldrich Vacuum Filtration Assembly gives you all the components you need including: funnel top, fritted glass funnel support, filtration flask, aluminum clamp, and silicone stopper.  The Acrodisc Syringe Filters offer high quality filtration for analytical samples, certified for HPLC to ensure low extractable and available in a broad range of membranes to meet sample compatibility requirements.

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