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E1768

5,8,11,14-Eicosatetraynoic acid

≥97%

Synonym(s):

ETYA, Octadehydroarachidonic acid

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5 mg
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$336.00

About This Item

Empirical Formula (Hill Notation):
C20H24O2
CAS Number:
1191-85-1
Molecular Weight:
296.40
UNSPSC Code:
12352106
NACRES:
NA.77
PubChem Substance ID:
24894432
MDL number:
MFCD00036967
Beilstein/REAXYS Number:
1798411
Assay:
≥97%
Form:
powder
Quality level:
200

$336.00

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biological source

synthetic (organic)

Quality Level

200

assay

≥97%

form

powder

mp

78-80 °C

solubility

ethanol: 50 mg/mL, clear, colorless to yellow

storage temp.

−20°C

SMILES string

CCCCCC#CCC#CCC#CCC#CCCCC(O)=O

InChI

1S/C20H24O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-5,8,11,14,17-19H2,1H3,(H,21,22)

InChI key

MGLDCXPLYOWQRP-UHFFFAOYSA-N

Gene Information

human ... ALOX15(246)

Biochem/physiol Actions

Eicosatetraynoic acid (ETYA) is a non-metabolizable analog of ω-6 arachidonic acid. ETYA is a strong activator of the human peroxisome proliferator-activated receptor α (PPARα).[1] It acts as an inhibitor of lipoxygenases (LOX)[2] and cyclooxygenases (COX).[3]
Eicosatetraynoic acid is a lipoxygenase and cyclooxygenase inhibitor.

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This Item
434741I4883F6513
5,8,11,14-Eicosatetraynoic acid ≥97%

Sigma-Aldrich

E1768

5,8,11,14-Eicosatetraynoic acid

ETYA Inhibits arachidonic acid uptake and the activities of arachidonic acid specific and non-specific acyl-CoA synthetases.

Sigma-Aldrich

434741

ETYA

Ibuprofen ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofen

Fusaric acid from Gibberella fujikuroi

Sigma-Aldrich

F6513

Fusaric acid

form

powder

form

solid

form

powder

form

powder

assay

≥97%

assay

≥95% (TLC)

assay

≥98% (GC)

assay

≥98% (TLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

solubility

ethanol: 50 mg/mL, clear, colorless to yellow

solubility

ethanol: 20 mg/mL, DMSO: soluble

solubility

ethanol: 50 mg/mL, clear, colorless to faintly yellow

solubility

ethanol: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

mp

78-80 °C

mp

-

mp

77-78  °C

mp

95-97  °C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
088K37972V
088K37972
088K37971
077H3781
075H3806

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Related Content

Product Information Sheet - E1768

Product Information Sheet

Parissa Taheri et al.
Journal of plant physiology, 167(3), 201-208 (2009-09-05)
Vitamins are plant growth regulators and activators of defense responses against pathogens. The cytomolecular mechanisms involved in the induction of resistance by chemicals especially vitamins on monocotyledonous plants are largely unknown. Here, we show that riboflavin, which acts as a
Kazuhiro Tamura et al.
Vascular pharmacology, 44(6), 411-416 (2006-05-03)
To address the role of prostaglandin E2 (PGE2) in tube formation of endothelial cells and the relationships between the action of PGE2 and vascular endothelial growth factor (VEGF), cultured human umbilical vein endothelial cells (HUVECs) were used to evaluate tube
Marcelo D Carattino et al.
The Journal of biological chemistry, 278(38), 36202-36213 (2003-07-03)
Epithelial Na+ channels (ENaCs) are regulated by the phospholipase A2 (PLA2) product arachidonic acid. Pharmacological inhibition of PLA2 with aristolochic acid induced a significant increase in amiloride-sensitive currents in Xenopus oocytes expressing ENaC. Arachidonic acid or 5,8,11,14-eicosatetraynoic acid (ETYA), a
View All Related Papers

Global Trade Item Number

SKUGTIN
E1768-5MG04061832785370
E1768-25MG04061832785363

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