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D7439

Dihydroartemisinin

analytical standard, mixture of α and β isomers

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50 mg
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$320.00

About This Item

Empirical Formula (Hill Notation):
C15H24O5
Molecular Weight:
284.35
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

$320.00


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grade

analytical standard

Quality Segment

assay

≥97% (TLC)

form

powder

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

C[C@H]1C(O)O[C@@]2([H])[C@@]3(OO4)[C@](CC[C@]4(C)O2)([H])[C@H](C)CC[C@]31[H]

InChI

1S/C15H24O5/c1-8-4-5-10-9(2)12(16)18-13-15(10)11(8)6-14(3,7-17-13)19-20-15/h8-13,16H,4-7H2,1-3H3/t8-,9-,10+,11+,12?,13+,14+,15+/m1/s1

InChI key

DJGUTYJDEZGRGH-NJEKVMANSA-N

General description

Antimalarial; antipsoriasis; anti-inflammatory.
Dihydroartemisinin is the major metabolite of the antimalarial agent, artemether. It is highly efficient against both drug-sensitive and drug-resistant strains of Plasmodium falciparum.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Preparation Note

artemisia plant extract

Disclaimer

Protect from light.

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storage temp.

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technique(s)

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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

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form

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form

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form

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form

powder


pictograms

FlameEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Chronic 2 - Org. Perox. C

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Anne Marijon et al.
Malaria journal, 13, 501-501 (2014-12-18)
Improving management of patients suffering from cerebral malaria is needed to reduce the devastating mortality and morbidity of the disease in endemic areas. Intravenous artesunate is currently the first-line treatment, but the lack of material and skills in the field
Zenglei Wang et al.
PloS one, 9(4), e93825-e93825 (2014-04-17)
Malaria elimination/eradication campaigns emphasize interruption of parasite transmission as a priority strategy. Screening for new drugs and vaccines against gametocytes is therefore urgently needed. However, current methods for sexual stage drug assays, usually performed by counting or via fluorescent markers
Selective determination, in plasma, of artemether and its major metabolite, dihydroartemisinin, by high-performance liquid chromatography with ultraviolet detection
Thomas GC, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 583(1), 131-136 (1992)



Global Trade Item Number

SKUGTIN
D7439-50MG04061833588536

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