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E8250

Esculin hydrate

≥98%

Synonym(s):

(-)-Esculin, 6,7-Dihydroxycoumarin 6-glucoside, Esculetin 6-β-D-glucoside

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About This Item

Empirical Formula (Hill Notation):
C15H16O9 · xH2O
CAS Number:
531-75-9
Molecular Weight:
340.28 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
24894668
UNSPSC Code:
12352201
EC Number:
208-517-5
MDL number:
MFCD00149492

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InChI key

CQYPGSKIFJFVDQ-QWFKVUSTSA-N

InChI

1S/C15H16O9.H2O/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17;/h1-4,10,12-17,19-21H,5H2;1H2/t10-,12-,13+,14-,15-;/m1./s1

assay

≥98%

Quality Level

200

SMILES string

O.OC[C@H]1O[C@@H](Oc2cc3C=CC(=O)Oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O

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1 of 4

This Item
02350PHL89659PHL80449
Esculin hydrate ≥98%

Sigma-Aldrich

E8250

Esculin hydrate

Esculin hydrate ≥98.0% (HPLC)

Sigma-Aldrich

02350

Esculin hydrate

Esculin phyproof® Reference Substance

PHL89659

Esculin

Esculetin phyproof® Reference Substance

PHL80449

Esculetin

assay

≥98%

assay

≥98.0% (HPLC)

assay

≥98.0% (HPLC)

assay

≥95.0% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

General description

Esculin hydrate has vasoprotective and venotonic properties.

Application

Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.

Biochem/physiol Actions

Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP4203
BCCN4958
BCCM0729
BCCM3554
BCCL2185

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Safety Properties and probiotic potential of Bacillus subtilis KATMIRA1933 and Bacillus amyloliquefaciens B-1895
AlGburi A, et al.
Advances in Microbiology, 6(6), 432-432 (2016)
The Clinician's Handbook of Natural Medicine (2015)
Safety Properties and probiotic potential of Bacillus subtilis KATMIRA1933 and Bacillus amyloliquefaciens B-1895
Ma QJ, et al.
Sci. Hortic., 220, 259-266 (2017)
S G Jenkins et al.
Journal of clinical microbiology, 49(11), 3947-3949 (2011-09-02)
A total of 142 stool specimens were evaluated for vancomycin-resistant enterococcus (VRE). Twenty-four-hour sensitivities and specificities, respectively, were 98% and 95% for Spectra VRE chromogenic agar (Remel, Lenexa, KS), 86% and 92% for bile esculin azide with vancomycin (BEAV; Remel)
Emiliano Ricardo Vasconcelos Rios et al.
Chemico-biological interactions, 188(1), 246-254 (2010-08-04)
This work describes the gastroprotective actions of esculin (6,7-dihydroxycoumarin-6-o-glucoside) against indomethacin- or ethanol-induced lesions and verifies the role of nitric oxide, ATP-dependent K(+) channels, prostaglandins, transient receptor potential vanilloid 1 and antioxidant effects in the gastroprotective mechanism of esculin in
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