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P7627

Sigma-Aldrich

6-Phosphogluconic acid barium salt hydrate

Grade VI, ≥90%, powder

Synonym(s):

6-PG-Ba, D-Gluconate 6-phosphate barium salt

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About This Item

Empirical Formula (Hill Notation):
C6H10Ba1.5O10P · xH2O
CAS Number:
921-62-0
Molecular Weight:
479.10 (anhydrous basis)
Beilstein/REAXYS Number:
1729373
EC Number:
213-069-9
UNSPSC Code:
12352201
PubChem Substance ID:
24898864
NACRES:
NA.25

biological source

synthetic (organic)

type

Grade VI

assay

≥90%

form

powder

color

white

storage temp.

−20°C

SMILES string

[O-]P(OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O)([O-])=O.[H]O[H].C

InChI

1S/C6H13O10P.CH4.H2O/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12;;/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15);1H4;1H2/p-3/t2-,3-,4+,5-;;/m1../s1

InChI key

VINGHIAQWNFZIR-ZBHRUSISSA-K

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General description

suitable for glucose-6-phosphate dehydrogenase tests

Application

6-Phosphogluconic acid has been used in a study to assess the biochemistry of Coxiella burnetti. It has also been used in a study to investigate the enzymatic transfer of hydrogen.

Preparation Note

Prepared by a modification of the procedure of Seegmiller, J.E., et al., J. Biol. Chem., 192, 175 (1951).

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Francisco Velázquez et al.
Journal of bacteriology, 186(24), 8267-8275 (2004-12-04)
Glucose and other C sources exert an atypical form of catabolic repression on the sigma54-dependent promoter Pu, which drives transcription of an operon for m-xylene degradation encoded by the TOL plasmid pWW0 in Pseudomonas putida. We have used a genetic
The enzymatic transfer of hydrogen. IX. The reactions catalyzed by glucose 6-phosphate dehydrogenase and 6-phosphogluconic dehydrogenase.
B K STERN et al.
The Journal of biological chemistry, 235, 205-208 (1960-01-01)
N Takahashi et al.
Journal of dental research, 89(12), 1383-1388 (2010-10-07)
Dental caries is initiated by demineralization of the tooth surface through acid production by sugar metabolism of supragingival plaque microflora. To elucidate the sugar metabolic system, we used CE-MS to perform metabolomics of the central carbon metabolism, the EMP pathway
Paolo A Calligari et al.
Proteins, 80(4), 1196-1210 (2012-01-26)
Nuclear magnetic resonance is used to investigate the backbone dynamics in 6-phosphogluconolactonase from Trypanosoma brucei (Tb6PGL) with (holo-) and without (apo-) 6-phosphogluconic acid as ligand. Relaxation data were analyzed using the model-free approach and reduced spectral density mapping. Comparison of
Teresa del Castillo et al.
Journal of bacteriology, 189(14), 5142-5152 (2007-05-08)
In this study, we show that glucose catabolism in Pseudomonas putida occurs through the simultaneous operation of three pathways that converge at the level of 6-phosphogluconate, which is metabolized by the Edd and Eda Entner/Doudoroff enzymes to central metabolites. When
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