M6020

D-(+)-Mannose

powder, BioReagent, suitable for cell culture

• Synonym(s): D-Mannopyranose
• Empirical Formula (Hill Notation): C₆H₁₂O₆
• CAS Number: 3458-28-4
• Molecular Weight: 180.16
• UNSPSC Code: 12352201
• NACRES: NA.75
• PubChem Substance ID: 24897068
• EC Number: 222-392-4
• Beilstein/REAXYS Number: 1564373
• MDL number: MFCD00064122

Properties

• biological source: plant (Spruce, Birch or Beech Wood, Glucose)
• Quality Segment: 300
• product line: BioReagent
• assay: ≥99%
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 133-140 °C (lit.)
• solubility: H₂O: 50 mg/mL
• application(s): advanced drug delivery; agriculture
• SMILES string: OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1
• InChI key: WQZGKKKJIJFFOK-QTVWNMPRSA-N

Description

General description

Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.

Application

Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.

D-(+)-Mannose has been used:

• as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa[1]
• as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
• in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines

Biochem/physiol Actions

Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)