G6893

α-D-Glucose 1,6-bisphosphate potassium salt hydrate

synthetic, ≥98% (TLC)

• Synonym(s): α-D-Glucose 1,6-diphosphate potassium salt hydrate
• Empirical Formula (Hill Notation): C₆H₁₀K₄O₁₂P₂ · xH₂O
• CAS Number: 91183-87-8
• Molecular Weight: 492.48 (anhydrous basis)
• MDL number: MFCD00150469
• UNSPSC Code: 12352201
• PubChem Substance ID: 24895278
• NACRES: NA.25

Properties

• biological source: synthetic
• assay: ≥98% (TLC)
• form: powder or crystals
• color: white
• solubility: water: 50 mg/mL, clear, colorless (OECD Test Guideline 105)
• cation traces: K: 28.5-33.5% (ICP)
• storage temp.: −20°C
• SMILES string: [K+].[K+].[K+].[K+].O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@H](OP([O-])([O-])=O)[C@@H]1O
• InChI: 1S/C6H14O12P2.4K/c7-3-2(1-16-19(10,11)12)17-6(5(9)4(3)8)18-20(13,14)15;;;;/h2-9H,1H2,(H2,10,11,12)(H2,13,14,15);;;;/q;4*+1/p-4/t2-,3-,4+,5-,6-;;;;/m1..../s1
• InChI key: OVRXVCAVDXBPQT-QMKHLHGBSA-J

Description

General description

α-D-Glucose 1,6-bisphosphate was found to be at a concentration of between 10 μm and 600 μm in various tissues including liver, brain and kidney.

Application

α-D-Glucose 1,6-bisphosphate is used in the identification, differentiation and characterization of α-phosphoglucomutase(s), β-phosphoglucomutase(s) and α- and β-hexoglucomutase(s).

Biochem/physiol Actions

Metabolite formed via the activity of Glucose-1,6-biphosphate synthase. Glucose-1,6-biphosphate (G-1,6-BP) acts as an inhibitor of hexokinase function and an activator of phosphofructokinase-1 and pyruvate kinase. G-1,6-BP also acts as a coenzyme for phosphoglucomutate and a cofactor for phosphopentomutase.

Other Notes

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)