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F2802

Fluvoxamine maleate

neuronal serotonin reuptake inhibitor, solid

Synonym(s):

(E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate

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Pack SizeSKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$105.00
50 mg

Available to ship TODAYfromMILWAUKEE

$464.00

About This Item

Empirical Formula (Hill Notation):
C15H21F3N2O2 · C4H4O4
CAS Number:
Molecular Weight:
434.41
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
solid
Quality level:

$105.00


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Product Name

Fluvoxamine maleate, solid

form

solid

Quality Level

solubility

H2O: soluble

originator

Solvay

storage temp.

2-8°C

SMILES string

COCCCC/C(C1=CC=C(C(F)(F)F)C=C1)=N\OCCN.OC(/C=C\C(O)=O)=O

InChI

1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-

InChI key

LFMYNZPAVPMEGP-PIDGMYBPSA-N

Application

Fluvoxamine maleate has been used as a test compound to determine the solubility and effective blood-brain barrier permeability.(2)

Biochem/physiol Actions

Fluvoxamine maleate is a selective neuronal serotonin reuptake inhibitor. It functions as an antidepressant and anti-obsessive agent. It is useful in treating obsessive compulsive disorder and panic disorder.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Solvay. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item
PHR1793F-040BP600
form

solid

form

solid

form

liquid

form

solid

Quality Level

200

Quality Level

300

Quality Level

300

Quality Level

-

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

H2O: soluble

solubility

-

solubility

-

solubility

-

originator

Solvay

originator

-

originator

-

originator

-

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), SLC6A4(6532)

Gene Information

human ... SLC6A4(6532)

Gene Information

human ... SLC6A4(6532)

Gene Information

human ... SLC6A4(6532)


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Mosby's Drug Reference for Health Professions null
Eiko Sunami et al.
Internal medicine (Tokyo, Japan), 51(10), 1187-1193 (2012-06-13)
Antidepressants have been recommended for the treatment of post-stroke depression (PSD). The purpose of this study was to evaluate the effect of fluvoxamine maleate, a selective serotonin re-uptake inhibitor (SSRI), on depressive state, sleep disturbance, and serum melatonin levels in
Yumi Sugimoto et al.
European journal of pharmacology, 696(1-3), 96-100 (2012-10-09)
We studied the involvement of the sigma(1) receptor in the antidepressant-like effects of the selective serotonin reuptake inhibitor (SSRI) fluvoxamine in DBA/2 mice using the forced swimming test. The effects of the selective sigma(1) receptor antagonist N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino) ethylamine (BD1047) at



Global Trade Item Number

SKUGTIN
F2802-10MG04061833613320
F2802-50MG04061832082073

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