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D9641

Deoxygalactonojirimycin hydrochloride

powder or solid, ≥98% (HPLC)

Synonym(s):

1,5-Dideoxy-1,5-imino-D-galactitol, Migalastat

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2 mg

Available to ship TODAYfromMILWAUKEE

$179.00

About This Item

Empirical Formula (Hill Notation):
C6H13NO4 · HCl
CAS Number:
75172-81-5
Molecular Weight:
199.63
UNSPSC Code:
12352200
PubChem Substance ID:
329798908
NACRES:
NA.32
MDL number:
MFCD00269962

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Product Name

Deoxygalactonojirimycin hydrochloride,

biological source

synthetic (organic)

Quality Segment

200

assay

≥98% (HPLC)

form

powder or solid

solubility

water: soluble 1 mg/mL

storage temp.

−20°C

SMILES string

Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5+,6-;/m1./s1

InChI key

ZJIHMALTJRDNQI-OLALXQGDSA-N

Application

Deoxygalactonojirimycin hydrochloride has been used as an α-galactosidase A inhibitor to assess the enzymatic activity of α-galactosidase A.[1][2] It has also been used as an α-galactosidase A inhibitor to study its effects on the mRNA levels in human embryonic kidney (HEK) cells and hippocampal neurons[3].

Biochem/physiol Actions

Deoxygalactonojirimycin hydrochloride is an inhibitor of α-galactosidase A.[1] Deoxygalactonojirimycin exhibits therapeutic effects against Fabry disease.[4]

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4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride Fluorogenic reagent

Sigma-Aldrich

D4784

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (GC)

assay

≥98% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

powder or solid

form

solid

form

powder

form

powder

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

water: soluble 1 mg/mL

solubility

H2O: slightly soluble 0.17 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.8 mg/mL, 0.1 M HCl: slightly soluble, DMSO: soluble, aqueous buffer pH > 5: soluble, ethanol: soluble

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

H2O: 50 mg/mL

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000554981
0000554344
0000554981
0000554344
0000511912

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Global Trade Item Number

SKUGTIN
D9641-2MG04061833270639

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