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biological source
plant (Croton tiglium L)
form
viscous liquid
density
0.94 g/mL at 25 °C (lit.)
functional group
ester
lipid type
oils
shipped in
ambient
storage temp.
room temp
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General description
Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature. Croton oil has a strong irritant property and is used along with phenol in some chemical peels. It also has a tumor promoting ability.
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma. Croton oil functions as a skin peeling agent.
application
Croton oil has been used to induce acute skin inflammation.
Croton oil has been used to induce inflammation in mouse ears.
Other Notes
Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
165.2 °F - closed cup
flash_point_c
74 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Certificates of Analysis (COA)
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Thekkuttuparambil Ananthanarayanan Ajith et al.
Journal of experimental therapeutics & oncology, 9(3), 207-215 (2011-11-11)
The roles of 7,12-dimethylbenz[a]anthracene (DMBA), a polycyclic aromatic hydrocarbon (PAH), and 12-O-tetradecanoylphorbol-13-acetate (TPA) a skin tumor promoter present in croton oil, are clearly implicated in the formation of skin papilloma. The effect of ethyl acetate extract of Phellinus rimosus, a
Sulaiman Hamizah et al.
Asian Pacific journal of cancer prevention : APJCP, 13(6), 2533-2539 (2012-09-04)
Annona muricata L (Annonaceae), commonly known as soursop has a long, rich history in herbal medicine with a lengthy recorded indigenous use. It had also been found to be a promising new anti-tumor agent in numerous in vitro studies. The
The inhibition of croton oil-promoted mouse skin tumorigenesis by steroid hormones
Belman S and Troll W
Cancer Research, 32(3), 450-454 (1972)
Aldair de França-Neto et al.
Natural product communications, 7(10), 1397-1400 (2012-11-20)
Croton argyrophylloides Muell. Arg. is widely used in Brazilian folk medicine to treat diabetes and venereal diseases. This study examined the acute toxicity and cytotoxicity of the essential oil of C. argyrophylloides (EOCA). In addition, vascular effects of the EOCA
An examination of the phenol-croton oil peel: Part I. Dissecting the formula
Hetter GP
Plastic and Reconstructive Surgery, 105(1), 227-239 (2000)
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