Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

B9636

S-Benzoylthiamine O-monophosphate

Synonym(s):

Benfotiamine

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
250 mg

Available to ship TODAYfromMILWAUKEE

$88.30

About This Item

Empirical Formula (Hill Notation):
C19H23N4O6PS
CAS Number:
22457-89-2
Molecular Weight:
466.45
NACRES:
NA.79
PubChem Substance ID:
24892147
UNSPSC Code:
12352116
EC Number:
245-013-4
MDL number:
MFCD00057343

$88.30

Available to ship TODAYDetails

​
Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥98% (TLC)

Quality Level

200

form

powder or crystals

color

white to off-white

storage temp.

2-8°C

SMILES string

Cc1ncc(CN(C=O)\C(C)=C(/CCOP(O)(O)=O)SC(=O)c2ccccc2)c(N)n1

InChI

1S/C19H23N4O6PS/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-29-30(26,27)28)31-19(25)15-6-4-3-5-7-15/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,26,27,28)/b17-13+

InChI key

BTNNPSLJPBRMLZ-GHRIWEEISA-N

General description

S-Benzoylthiamine O-monophosphate (Benfotiamine) is an amphiphilic S-acyl thiamine derivative. It is a lipid-soluble vitamin. Benfotiamine contains a thiazole ring. Benfotiamine has a greater bioavailability than thiamine.

Application

S-Benzoylthiamine O-monophosphate has been used to determine its effect on ischemia and reperfusion in skeletal muscles of rat.

Biochem/physiol Actions

S-Benzoylthiamine O-monophosphate (Benfotiamine) is a therapeutic agent. It helps in the prevention of diabetic complications such as, retinopathy, neuropathy and nephropathy. Benfotiamine inhibits the synthesis of glycation end products (AGEs) in diabetes. Benfotiamine is considered as a nutraceutical product for the prevention of diabetic neuropathy.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
SMB00294F6750T4625
S-Benzoylthiamine O-monophosphate

Sigma-Aldrich

B9636

S-Benzoylthiamine O-monophosphate

Thiamine mononitrate ≥98% (HPLC)

Sigma-Aldrich

SMB00294

Thiamine mononitrate

Riboflavin 5′-monophosphate sodium salt hydrate 70-79% (fluorimetric)

Sigma-Aldrich

F6750

Riboflavin 5′-monophosphate sodium salt hydrate

Thiamine hydrochloride reagent grade, ≥99% (HPLC)

Sigma-Aldrich

T4625

Thiamine hydrochloride

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

70-79% (fluorimetric)

assay

≥99% (HPLC)

form

powder or crystals

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

color

white to off-white

color

white to off-white

color

-

color

white

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000491943
0000491943
0000491060
0000491060
0000480425

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Umesh C S Yadav et al.
Free radical biology & medicine, 48(10), 1423-1434 (2010-03-12)
This study was designed to investigate the molecular mechanisms by which benfotiamine, a lipid-soluble analogue of vitamin B1, affects lipopolysaccharide (LPS)-induced inflammatory signals leading to cytotoxicity in the mouse macrophage cell line RAW264.7. Benfotiamine prevented LPS-induced apoptosis, expression of the
Xiaoli Pan et al.
Neuroscience bulletin, 32(6), 591-596 (2016-10-04)
To date, we still lack disease-modifying therapies for Alzheimer's disease (AD). Here, we report that long-term administration of benfotiamine improved the cognitive ability of patients with AD. Five patients with mild to moderate AD received oral benfotiamine (300 mg daily) over
Pitchai Balakumar et al.
Pharmacological research, 61(6), 482-488 (2010-03-02)
Thiamine, known as vitamin B(1), plays an essential role in energy metabolism. Benfotiamine (S-benzoylthiamine O-monophoshate) is a synthetic S-acyl derivative of thiamine. Once absorbed, benfotiamine is dephosphorylated by ecto-alkaline phosphatase to lipid-soluble S-benzoylthiamine. Transketolase is an enzyme that directs the
View All Related Papers

Global Trade Item Number

SKUGTIN
B9636-250MG04061833443866

Questions

Reviews

No rating value

Active Filters