44270

trans,trans-Farnesyl pyrophosphate ammonium salt

≥95.0% (HPLC)

• Synonym(s): (E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt, Farnesyl diphosphate ammonium salt
• Empirical Formula (Hill Notation): C₁₅H₂₈O₇P₂ · xNH₃
• Molecular Weight: 382.33 (free acid basis)
• NACRES: NA.25
• PubChem Substance ID: 329756482
• UNSPSC Code: 12352212
• Beilstein/REAXYS Number: 2482197
• Assay: ≥95.0% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥95.0% (HPLC)
• form: solid
• storage temp.: −20°C
• SMILES string: N.C\C(C)=C\CC\C(C)=C\CC\C(C)=C\COP(O)(=O)OP(O)(O)=O
• InChI: 1S/C15H28O7P2.H3N/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18;/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18);1H3/b14-9+,15-11+;
• InChI key: CPYJTMLHKIWGDF-NDHHSALASA-N

Description

Application

Farnesyl diphosphate ammonium salt may be used to study the posttranslational process known as farnesylation that is used to modify important proteins such as the Ras oncogene.

Biochem/physiol Actions

Farnesyl pyrophosphate is a key intermediate in the biosynthesis of more complex sesquiterpenoids, higher terpenoids, and steroids[1] and different biological functions have been discovered for FPP and the corresponding alcohol farnesol[2][3][4][5][6][7]. FPP plays an important role in the posttranslational processing of Ras proteins. Mutated forms of Ras are associated with human cancer and are therefore investigated in cancer research[5][6].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable