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N1892

Nadolol

analytical standard

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1 g

Available to ship TODAYfromMILWAUKEE

$84.40
5 g

Available to ship TODAYfromMILWAUKEE

$897.00

About This Item

Empirical Formula (Hill Notation):
C17H27NO4
CAS Number:
42200-33-9
Molecular Weight:
309.40
NACRES:
NA.24
PubChem Substance ID:
329818591
UNSPSC Code:
41116107
EC Number:
255-706-3
MDL number:
MFCD00079476

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grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12

InChI

1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3/t12?,14-,15+/m1/s1

InChI key

VWPOSFSPZNDTMJ-UCWKZMIHSA-N

Gene Information

human ... ADRB1(153), ADRB2(154)

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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

format

neat

format

neat

format

neat

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

grade

analytical standard

grade

analytical standard

grade

-

grade

analytical standard

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

forensics and toxicology
pharmaceutical (small molecule)

Gene Information

human ... ADRB1(153), ADRB2(154)

Gene Information

human ... NR3C1(2908)

Gene Information

rat ... Ar(24208)

Gene Information

human ... AR(367)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

β-Adrenergic blocker

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP4853
BCCN6401
BCCJ9822
BCCL0909
BCCG6502

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Priya Chockalingam et al.
Journal of the American College of Cardiology, 60(20), 2092-2099 (2012-10-23)
The purpose of this study was to compare the efficacy of beta-blockers in congenital long QT syndrome (LQTS). Beta-blockers are the mainstay in managing LQTS. Studies comparing the efficacy of commonly used beta-blockers are lacking, and clinicians generally assume they
Sarah Maud Fischer et al.
International journal of pharmaceutics, 422(1-2), 52-58 (2011-10-27)
The compatibility of fasted state simulated intestinal fluid (FaSSIF) in drug permeation studies employing the phospholipid vesicle-based permeation assay (PVPA) model was confirmed by a set of different integrity indicators. Neither calcein permeability nor electrical resistance were found significantly changed
Sarah Maud Fischer et al.
The Journal of pharmacy and pharmacology, 63(8), 1022-1030 (2011-07-02)
The aim of this study was to determine the influence of nonionic surfactants on drug permeability using the phospholipid vesicle-based permeation assay (PVPA), which excludes other than trans-membrane diffusion pathways. Barrier integrity was monitored both by electrical resistance and permeability
Ling Wang et al.
The Science of the total environment, 426, 289-295 (2012-04-17)
Beta-blockers, prescribed for the treatment of high blood pressure and for long-term use after a heart attack, have been detected in surface and ground waters. This study examines the photochemical fate of three beta-blockers, atenolol, metoprolol, and nadolol. Hydrolysis accounted
Alessandra Besana et al.
Journal of cardiovascular pharmacology, 59(3), 249-253 (2011-10-28)
Beta-adrenergic receptor antagonists (β-blockers) are the therapy of choice for the long QT syndrome but their efficacy is not homogeneous: propranolol and nadolol are the most effective, whereas metoprolol is associated with more treatment failures. Propranolol has a blocking effect
View All Related Papers

Global Trade Item Number

SKUGTIN
N1892-5G04061833652671
N1892-1G04061834109914

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