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78666

Taxifolin

analytical standard

Synonym(s):

(2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone, (2R,3R)-Dihydroquercetin

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Pack SizeSKUAvailabilityPrice
25 mg

Estimated to ship onJune 05, 2026fromMILWAUKEE

$82.80
100 mg

Available to ship TODAYfromMILWAUKEE

$278.00

About This Item

Empirical Formula (Hill Notation):
C15H12O7
CAS Number:
Molecular Weight:
304.25
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-543-4
Beilstein/REAXYS Number:
5299277
MDL number:

$82.80


Estimated to ship onJune 05, 2026Details


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grade

analytical standard

Quality Segment

assay

≥85% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3

InChI

1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1

InChI key

CXQWRCVTCMQVQX-LSDHHAIUSA-N

General description

Taxifolin is a plant flavonoid, which may find applications in the treatment of coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction and sequelae.

Application

Taxifolin can be used as a reference standard for the determination of taxifolin in plasma of rabbit using high performance liquid chromatography technique(HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
PHL892844225116654
application(s)

food and beverages

application(s)

-

application(s)

food and beverages

application(s)

food and beverages

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

grade

analytical standard

grade

primary reference standard

grade

analytical standard

grade

analytical standard

assay

≥85% (HPLC)

assay

≥95.0% (HPLC)

assay

≥99% (HPLC)

assay

≥98% (HPLC)

format

neat

format

-

format

neat

format

neat


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.


Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid
Theriault A, et al.
Journal of Lipid Research, 41, 1969-1979 (2000)
Sharad Verma et al.
Journal of molecular graphics & modelling, 37, 27-38 (2012-05-23)
Hsp90 (heat shock protein 90), a molecular chaperone, stabilizes more than 200 mutated and over expressed oncogenic proteins in cancer development. Cdc37 (cell division cycle protein 37), a co-chaperone of Hsp90, has been found to facilitate the maturation of protein
Jan Vacek et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 899, 109-115 (2012-06-06)
Liquid chromatography (LC) on various stationary phases was used for the metabolite profile analysis of quercetin, rutin, isoquercitrin and taxifolin. The metabolites were obtained using an in vitro model system of human and rat hepatocytes in the form of cell



Global Trade Item Number

SKUGTIN
530549-5G04061833637043
78666-25MG-F04061835561193
78666-100MG-F04061832947082

Questions

1–3 of 3 Questions  
  1. What is the long term storage temperature for Taxifolin (78666)

    1 answer
    1. Please see the product label for the recommended storage conditions. If no information is provided on the label, this means that it can be stored at Room Temperature (RT). As of this writing, we do recommend RT storage for Product 78666.

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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