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252522

Crotononitrile, mixture of cis and trans

99%

Synonym(s):

2-Butenenitrile, mixture of cis and trans

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Pack SizeSKUAvailabilityPrice
5 mL

Available to ship TODAYfromMILWAUKEE

$40.80
100 mL

Available to ship TODAYfromMILWAUKEE

$359.00
500 mL

Available to ship TODAYfromMILWAUKEE

$1,630.00
$1,222.50

About This Item

Linear Formula:
CH3CH=CHCN
CAS Number:
Molecular Weight:
67.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-335-1
Beilstein/REAXYS Number:
1719747
MDL number:
Assay:
99%
Form:
liquid

$40.80


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Quality Level

assay

99%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

120-121 °C (lit.)

density

0.824 g/mL at 25 °C (lit.)

functional group

nitrile

SMILES string

C\C=C\C#N

InChI

1S/C4H5N/c1-2-3-4-5/h2-3H,1H3/b3-2+

InChI key

NKKMVIVFRUYPLQ-NSCUHMNNSA-N

General description

Neurotoxic properties of crotononitrile have been investigated[1]. Mechanism of the Baylis-Hillman reaction of crotononitrile and benzaldehyde in the presence of 1,4-diazabicyclo[2,2,2]octane (catalyst) has been investigated.

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27980338958143774
assay

99%

assay

≥99.5% (GC)

assay

80%

assay

99%

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

refractive index

n20/D 1.419 (lit.)

refractive index

n20/D 1.437

refractive index

n20/D 1.46 (lit.)

refractive index

n20/D 1.38 (lit.)

form

liquid

form

liquid

form

liquid

form

liquid

density

0.824 g/mL at 25 °C (lit.)

density

0.853 g/mL at 20 °C (lit.)

density

1.089 g/mL at 25 °C (lit.)

density

0.65 g/mL at 25 °C (lit.)

bp

120-121 °C (lit.)

bp

101-102 °C (lit.)

bp

-

bp

37 °C (lit.)


pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

60.8 °F - closed cup

flash_point_c

16 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Eduardo Balbuena et al.
Toxicology and applied pharmacology, 187(2), 89-100 (2003-03-22)
The neurotoxic compound crotononitrile has two isomeric forms, cis and trans. We compared the effects of these two isomers isolated by distillation from the commercially available mixture. Adult male Long-Evans rats were administered vehicle control, cis-crotononitrile (80, 100, and 120
H Tanii et al.
Brain research, 868(1), 141-146 (2000-06-08)
Allylnitrile and crotononitrile induce behavioral abnormalities in mice. To explore the possible involvement of the vestibular system in these behavioral abnormalities, the expression of Fos protein, used as an indicator of neuronal activity, was examined within various brain structures in
Pere Boadas-Vaello et al.
Toxicology and applied pharmacology, 225(3), 310-317 (2007-09-20)
Several alkylnitriles are toxic to sensory systems, including the vestibular system, through yet undefined mechanisms. This study addressed the hypothesis that the vestibular toxicity of cis-crotononitrile depends on CYP2E1-mediated bioactivation. Wild-type (129S1) and CYP2E1-null female mice were exposed to cis-crotononitrile



Global Trade Item Number

SKUGTIN
252522-100ML04061825973425
252522-500ML04061836826017
252522-5ML04061825973432

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